ArticlePediatric pulmonology2025
Time Toxicity: Quantifying Healthcare Utilization Attributable to Pediatric Home Ventilation.
Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- The Impact of COronaVIrus Disease of 2019 Pandemic on Home Health Nursing Availability in Pediatric Patients After Tracheostomy Placement.Pediatric pulmonology · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveDetermine the "time toxicity," or time burden patients experience when pursuing health-related interventions, of pediatric invasive home ventilation. STUDY
designRetrospective chart review.
methodsWe identified all patients from a single neonatal intensive care unit who received a tracheostomy with/without home ventilation (T + /-HV) from 2016 to 2024. After matching the gestational week distribution of this cohort, five controls were randomly selected for each T + /-HV patient. Healthcare encounters in the electronic medical record were compared for the cohort versus controls. All encounters on a single calendar day were counted as 1 day of healthcare utilization.
resultsWe identified 62 patients with T + /-HV and 310 controls. Mortality was 35.5% among the T + /-HV cohort and 9% among controls. Median inpatient hospitalizations (7.0 vs. 2.0), total healthcare encounters (64.0 vs. 15.5), days of healthcare utilization (296 vs. 46), and healthcare utilization ratio (0.4 vs. 0.1) were all significantly higher for the T + /-HV cohort compared with controls. Differences were greatest in the first year of life. Among survivors in the T + /-HV cohort, decannulated patients had significantly greater healthcare utilization than those not decannulated.
conclusionsThis proof-of-concept analysis quantified "time toxicity" for pediatric invasive home ventilation and demonstrated that neonates who receive a tracheostomy during their initial admission spent over half of all days in their first 2 years of life interacting with the healthcare system. "Time toxicity" could add objective information to better prepare families for what life looks like with a child using a ventilator at home.
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