ArticleFrontiers in pharmacology2025
Bletilla oligosaccharides improved 5-fluorouracil-induced intestinal mucositis in mice by activating NF-κB signalling pathway and regulating intestinal microbiota.
Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Article
- Anti-Inflammatory Potential ofPharmaceuticals (Basel, Switzerland) · 2026Review
- Article
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6 authors.
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Abstract
Introduction: The Bletilla oligosaccharides (BO) are active compounds extracted from Methods: BO were purified from DEAE52 cellulose. The structure of BO were characterised by HPGPC, GC-MS and NMR. Results: Structural characterisation showed that BO were the neutral polysaccharide composed mainly of glucose and mannose. The backbone of BO consisted of→4)-β-Manp-(1→, →4)-β-Glcp-(1→ and small →3,4)-α-Manp-(1→. The results of the Conclusion: BO can relieve the progress of intestinal mucositis by relieving inflammation, protecting the intestinal epithelial barrier and regulating the intestinal microbiota. These data provide experimental evidence for the application of BO in chemotherapeutic intestinal mucositis.
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