ReviewPeerJ2025
Understanding uremic cardiomyopathy: from pathogenesis to diagnosis and the horizon of therapeutic innovations.
Review in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Lipid Disorders in Patients with Renal Failure: Role in Cardiovascular Events and Progression of Chronic Kidney Disease.Life (Basel, Switzerland) · 2026Review
- Impact of chronic kidney disease on clinical outcomes among patients with atrial fibrillation following percutaneous left atrial appendage occlusion: a multicentre cohort study.European heart journal open · 2026Article
- Interpreting a Thick Myocardium on Cardiac MR: A Practical Guide for Radiologists.Journal of the Korean Society of Radiology · 2026Review
- Biomarkers for Chronic Kidney Disease: An Updated Review of Innovative Detection Approaches.Current aging science · 2026Review
- Amelioration of CKD-induced cardiomyocyte hypertrophy by pegmolesatide: involvement of JAK2/STAT3 inhibition and mitochondrial protection.Frontiers in pharmacology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Uremic cardiomyopathy (UC) is a significant cardiovascular complication in individuals with end-stage renal disease. This review aims to explore the multifaceted landscape of UC, including the key pathophysiological mechanisms, diagnostic challenges, and current therapeutic approaches. The prevalence of cardiac hypertrophy, as a hallmark of UC, is highlighted and some new insights to its intricate pathogenesis, involving uremic toxins, oxidative stress, and inflammatory responses is elucidated. Diagnostic complexities, including the absence of specific biomarkers, are discussed, and the need for advanced imaging modalities and emerging diagnostic strategies are emphasized. Current therapeutic interventions, although lacking specificity, are addressed, paving its way to the potential future directions in targeted therapies. The review concludes new insights into the critical importance of ongoing research and technological advancements which will enhance early detection, precision treatment, and ultimately improve outcomes for individuals with UC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.