Evidence map›Paper›PMID 40183046›Full record

ArticlePeerJ2025

Chaetoglobosin A induces apoptosis in T-24 human bladder cancer cells through oxidative stress and MAPK/PI3K-AKT-mTOR pathway.

Jia Song, Jinyu Qiao, Mingxue Chen, Jiahui Li, Jixia Wang, Dayong Yu, Huachuan Zheng, Liying Shi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Tissue barriers · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jia Song *School of Life and Health, Dalian University, Dalian, China.
Jinyu QiaoSchool of Life and Health, Dalian University, Dalian, China.
Mingxue ChenSchool of Life and Health, Dalian University, Dalian, China.
Jiahui LiSchool of Life and Health, Dalian University, Dalian, China.
Jixia WangDalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.
Dayong Yu *School of Basic Medical Sciences, Chengde Medical University, Chengde, China.
Huachuan ZhengDepartment of Oncology, The Affiliated Hospital of Chengde Medical University, Chengde, China.
Liying ShiSchool of Life and Health, Dalian University, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chaetoglobosin A (ChA) is an antitumor compound produced by

Indexed as

Antineoplastic AgentsApoptosisIndole AlkaloidsOxidative StressUrinary Bladder NeoplasmsCell Line, TumorCell MovementCell ProliferationHumansMAP Kinase Signaling SystemMembrane Potential, MitochondrialPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReactive Oxygen SpeciesSignal TransductionTOR Serine-Threonine KinasesAntineoplastic AgentschaetoglobosinsIndole AlkaloidsMTOR protein, humanPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReactive Oxygen SpeciesTOR Serine-Threonine KinasesApoptosisChaetoglobosin AMAPK pathwayPI3K-AKT-mTOR pathwayReactive oxygen species

Identifiers

PMID40183046
PMCPMC11967413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.