Evidence map›Paper›PMID 40183040›Full record

ArticlePeerJ2025

Evaluation of optic nerve sheath diameter in acute stroke: pre- and post-thrombolytic assessment.

Erdem Sivas, Nese Colak, Basak Bayram, Muhammet Kursat Simsek, Nuri Karabay, Vesile Ozturk

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Erdem SivasDepartment of Emergency Medicine, Mardin Public Hospital, Mardin, Turkey.
Nese ColakDepartment of Emergency Medicine, University of Health Sciences Turkey, Izmir, Turkey.ORCID 0000-0001-6821-9031
Basak BayramDepartment of Emergency Medicine, Kocaeli City Hospital, Kocaeli, Turkey.
Muhammet Kursat SimsekDepartment of Radiology, Manisa Provincial Health Directorate Merkezefendi Public Hospital, Manisa, Turkey.
Nuri KarabayDepartment of Radiology, Dokuz Eylul University, Faculty of Medicine, Izmir, Turkey.
Vesile OzturkDepartment of Neurology, Dokuz Eylul University, Faculty of Medicine, Izmir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intracranial pressure increases due to ischemic infarction caused by stroke. This study aimed to evaluate the pre-thrombolytic and post-thrombolytic optic nerve sheath diameter (ONSD) measurements in predicting clinical outcomes and complications for stroke patients. Methods: ONSD was measured on computed tomography (CT) scans. The average ONSD (aONSD) was calculated from the right and left eyes. Pre-thrombolytic (ONSD-0) and post-thrombolytic (ONSD-24) values were compared according to right Results: Ninety-three patients were enrolled; 52.7% were female, and the mean age of all participants was 76 years. The aONSD-24 values were higher than the aONSD-0 values (5.5 ± 0.7 mm and 5.3 ± 0.7 mm, respectively, Conclusions: ONSD values on 24-h brain CT scans were higher than admission values in acute stroke patients receiving thrombolytic therapy, irrespective of the right or left side, stroke-affected side, presence of complications, and mortality. However, ONSD is not a sufficient parameter for predicting complications and death.

Indexed as

Optic NerveStrokeThrombolytic TherapyAgedAged, 80 and overFemaleHumansMaleMiddle AgedTomography, X-Ray ComputedAcute ischemic strokeMortalityOptic nerve sheath diameterStroke complicationThrombolytic treatment

Identifiers

PMID40183040
PMCPMC11967433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.