Evidence map›Paper›PMID 40182964›Full record

ArticleSaudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society

Juvenile idiopathic arthritis and associated uveitis: A review of pathogenesis, diagnosis, and management.

Costanza Barresi, Francesco Baldo, Matteo Menean, Achille Marino, Stefania Costi, Cecilia B Chighizola, Roberto F Caporali, Elisabetta Miserocchi

Abstract read
In one paragraph

Article in Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Ocular Clues in Musculoskeletal Disorders: A Narrative Review for Orthopaedic Specialists.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
    Review
  3. Article
  4. Article
  5. Biosimilars in Adult and Pediatric Noninfectious Uveitis.Clinical ophthalmology (Auckland, N.Z.) · 2026
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Costanza BarresiDepartment of Ophthalmology IRCCS San Raffaele Scientific Institute, Milan, Italy.
Francesco BaldoDepartment of Pediatric Rheumatology, Unit of Pediatric Rheumatology, ASST G. Pini-CTO, Milan, Italy.
Matteo MeneanDepartment of Ophthalmology IRCCS San Raffaele Scientific Institute, Milan, Italy.
Achille MarinoDepartment of Pediatric Rheumatology, Unit of Pediatric Rheumatology, ASST G. Pini-CTO, Milan, Italy.
Stefania CostiDepartment of Pediatric Rheumatology, Unit of Pediatric Rheumatology, ASST G. Pini-CTO, Milan, Italy.
Cecilia B ChighizolaDepartment of Pediatric Rheumatology, Unit of Pediatric Rheumatology, ASST G. Pini-CTO, Milan, Italy.
Roberto F CaporaliDepartment of Pediatric Rheumatology, Unit of Pediatric Rheumatology, ASST G. Pini-CTO, Milan, Italy.
Elisabetta MiserocchiDepartment of Ophthalmology IRCCS San Raffaele Scientific Institute, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Juvenile idiopathic arthritis (JIA) is the most common rheumatologic disorder in children, posing significant physical and emotional challenges due to its chronic nature and the need for prolonged immunosuppressive therapies. Uveitis is the most common extra-articular manifestation of JIA, and it can be a sight-threatening condition. Despite advances in biologic treatments, JIA continues to present substantial therapeutic challenges, necessitating multiple treatment attempts and close monitoring for secondary failures. JIA-associated uveitis remains one of the most challenging and aggressive types of uveitis, particularly in children, due to its early onset, chronicity, and limited therapeutic responses despite new treatments. Early recognition and prompt treatment of both arthritis and uveitis are essential for achieving sustained remission and preventing complications. Effective management of JIA-uveitis requires a collaborative approach between pediatric rheumatologists and ophthalmologists to ensure timely assessments, regular screenings, and necessary therapy adjustments. This integrated care approach is crucial for achieving optimal outcomes. Therefore, this review aims to extensively analyze the pathogenesis, diagnosis, and therapy of JIA and its associated uveitis.

Indexed as

Diagnosisjuvenile idiopathic arthritistherapyuveitis

Identifiers

PMID40182964
PMCPMC11964343

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.