Evidence map›Paper›PMID 40182958›Full record

ReviewFrontiers in reproductive health2025

The integration of artificial intelligence in assisted reproduction: a comprehensive review.

Pragati Kakkar, Shruti Gupta, Kasmiria Ioanna Paschopoulou, Ilias Paschopoulos, Ioannis Paschopoulos, Vassiliki Siafaka, Orestis Tsonis

Abstract readReview
In one paragraph

Review in Frontiers in reproductive health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
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  6. Evolving PCOS Management: From Symptom Control to Phenotype-Targeted Therapy.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pragati Kakkar *Assisted Conception Unit, Guy's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Shruti Gupta *Assisted Conception Unit, Guy's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Kasmiria Ioanna Paschopoulou *Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Ilias Paschopoulos *School of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece.
Ioannis Paschopoulos *School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece.
Vassiliki Siafaka *School of Health Sciences, University of Ioannina, Ioannina, Greece.
Orestis Tsonis *Assisted Conception Unit, Guy's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial Intelligence (AI) has emerged as a transformative force in healthcare, with its integration into assisted reproduction technologies representing a notable milestone. The utilization of AI in assisted reproduction is rooted in the persistent challenge of optimizing outcomes. Despite years of progress, success rates in assisted reproductive techniques remain a concern. The current landscape of AI applications demonstrates significant potential to revolutionize various facets of assisted reproduction, including stimulation protocol optimization, embryo formation prediction, oocyte and sperm selection, and live birth prediction from embryos. AI's capacity for precise image-based analysis, leveraging convolutional neural networks, stands out as a promising avenue. Personalized treatment plans and enhanced diagnostic accuracy are central themes explored in this review. AI-driven healthcare products demonstrate the potential for real-time, adaptive health programs, fostering improved communication between patients and healthcare teams. Continuous learning systems to address challenges associated with biased training data and the time required for accurate decision-making capabilities to develop is imperative. Challenges and ethical considerations in AI-assisted conception as evident when taking into consideration issues such as the lack of legislation regulating AI in healthcare, a fact that emphasizes the need for transparency and equity in the development and implementation of AI technologies. The regulatory framework, both in the UK and globally, is making efforts to balance innovation with patient safety. This paper delves into the revolutionary impact of Artificial Intelligence (AI) in the realm of assisted reproduction technologies (ART). As AI continues to evolve, its application in the field of reproductive medicine holds great promise for improving success rates, personalized treatments, and overall efficiency. This comprehensive review explores the current state of AI in assisted reproduction, its potential benefits, challenges, and ethical considerations.

Indexed as

artificial intelligenceembryo selection algorithmsethicsIVFpatient-centredpersonalised carepredictive modellingreproductive medicine

Identifiers

PMID40182958
PMCPMC11965653

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.