Evidence map›Paper›PMID 40182885›Full record

ArticleJournal of hand surgery global online2025

Beyond Amputation: Functional Restoration after Upper-Extremity Limb Loss.

Jonathan T Bricker, Kazimir R Bagdady, Lindsay E Janes, Jason M Souza, Gregory A Dumanian, Jason H Ko

Abstract read
In one paragraph

Article in Journal of hand surgery global online, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jonathan T BrickerDivision of Plastic & Reconstructive Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Kazimir R BagdadyDivision of Plastic & Reconstructive Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Lindsay E JanesDivision of Plastic & Reconstructive Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Jason M SouzaDepartments of Plastic and Reconstructive Surgery and Orthopedic Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.
Gregory A DumanianDivision of Plastic & Reconstructive Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Jason H KoDivision of Plastic & Reconstructive Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several factors have contributed to poor quality of life outcomes for upper-extremity amputees. In recent decades, the advancements in both surgical procedures and prosthetics have been aimed at both improving the function and quality of life of amputees. Targeted muscle reinnervation, regenerative peripheral nerve interfaces, agonist-antagonist myoneural interfaces, free tissue transfers, and limb transplantation are chief among the surgical options available for improved sensorimotor function in residual and prosthetic limbs. New technologies such as cuff electrodes, intraneural filaments, and various osseointegrated prosthesis systems are used either alone or in concert with these operative techniques. Procedural and technological advancements will continue to push the limits of functional restoration after upper-extremity limb loss.

Indexed as

Free tissue transferOsseointegrationRegenerative peripheral nerve interfacesTargeted muscle reinnervationUpper-extremity amputation

Identifiers

PMID40182885
PMCPMC11963025

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.