Evidence map›Paper›PMID 40182721›Full record

ArticleBiology of sport2025

Late-stage rehabilitation effects do not differ between quadriceps and hamstring tendon autograft after anterior cruciate ligament reconstruction: a multicentre propensity score-matched case-control intervention trial.

Daniel Niederer, Matthias Keller, Wolf Petersen, Natalie Mengis, Christian Eberle, Daniel Guenther, Georg Brandl, Björn H Drews, Tobias Engeroff, Lutz Vogt and 2 more

Abstract read
In one paragraph

Article in Biology of sport, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Daniel NiedererInstitute of Occupational, Social and Environmental Medicine, Goethe University Frankfurt.
Matthias KellerOSINSTITUT ortho & sport, Munich, Germany.
Wolf PetersenKlinik für Orthopädie und Unfallchirurgie, Berlin, Germany.
Natalie MengisArcus Sportklinik, Pforzheim, Germany.
Christian EberleArcus Sportklinik, Pforzheim, Germany.
Daniel GuentherDepartment of Orthopaedic Surgery, Trauma Surgery, and Sports Medicine, Cologne Merheim Medical Center, Witten/Herdecke University, Germany.
Georg BrandlDepartment of Orthopaedic Surgery II, Herz-Jesu Krankenhaus, Vienna, Austria.
Björn H DrewsSt. Vinzenz Clinic Allgäu, Pfronten, Germany.
Tobias EngeroffInstitute of Occupational, Social and Environmental Medicine, Goethe University Frankfurt.
Lutz VogtDepartment of Sports Medicine and Exercise Physiology; Goethe University Frankfurt, Frankfurt am Main, Germany.
David A GronebergInstitute of Occupational, Social and Environmental Medicine, Goethe University Frankfurt.
Thomas SteinDepartment of Sports Medicine and Exercise Physiology; Goethe University Frankfurt, Frankfurt am Main, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Late-stage rehabilitation interventions after an anterior cruciate ligament (ACL) reconstruction are under-researched, inter alia regarding potential differences in rehabilitation effects between autograft types. This study determined the effectiveness of a specific, late-stage rehabilitation to usual care after ACL reconstructions in patients with a quadriceps versus such with a hamstring tendon autograft. In this multicentre case-control intervention study, participants aged 18-35 years were included at the end of their formal rehabilitation (mean 8.1 months) after ACL reconstruction. Twenty-four cases with an arthroscopically assisted, anatomic ipsilateral quadriceps femoris tendon autograft and two numerically equal hamstring tendon reconstructed propensity score-matched groups were compared. Matching variables were gender, age, Tegner activity scale, plus, once, the time since reconstruction and once the functional capacity at intervention onset. All participants performed a 5-month performance enhancing intervention. All outcomes were measured once a month. Self-reported outcomes such as knee function (The Knee injury and Osteoarthritis Outcome Score (KOOS) Sport as the main self-reported outcome) were followed by a series of hop and jump tests. The front hops for distance (outcome: hopping distance) was the primary outcomes of the study. Linear mixed models were calculated using change scores. All participants were analysed. No group*time interaction effect could be identified in the two main outcomes KOOS SPORT and front hop for distance. Furthermore, with the exception of the self-reported all-day function, no outcome displayed any between-group differences in the trainability, either. The return-to-sport success took a mean time of 3.8 months after study commencement; the success rates ranged between 80% and 83% and were not different between groups. Being reconstructed with a hamstrings or with a quadriceps tendon autograft had no impact on the late-stage rehabilitation effects after an ACL rupture. Both graft choices enable comparably favourable functional outcomes and return-to-sport success rates. Conversely, no recommendation can be derived with regard to the selection of either a hamstring or a quadriceps autograft type. The decision must be undertaken individually and based on other factors.

Indexed as

AutograftFunctional capacityInterventionPropensity scoreRe-injuryReturn to sportsRTS

Identifiers

PMID40182721
PMCPMC11963125

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.