Evidence map›Paper›PMID 40182551›Full record

ArticleFrontiers in plant science2025

Mapping and characterization of a novel powdery mildew resistance locus (PM2) in

Soren Seifi, Keegan M Leckie, Ingrid Giles, Taylor O'Brien, John O MacKenzie, Marco Todesco, Loren H Rieseberg, Gregory J Baute, Jose M Celedon

Abstract read
In one paragraph

Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Genetic Advances inPlants (Basel, Switzerland) · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Soren Seifi *Breeding and Genetics Department, Aurora Cannabis, Inc., Comox, BC, Canada.
Keegan M Leckie *Breeding and Genetics Department, Aurora Cannabis, Inc., Comox, BC, Canada.
Ingrid GilesBreeding and Genetics Department, Aurora Cannabis, Inc., Comox, BC, Canada.
Taylor O'BrienBreeding and Genetics Department, Aurora Cannabis, Inc., Comox, BC, Canada.
John O MacKenzieBreeding and Genetics Department, Aurora Cannabis, Inc., Comox, BC, Canada.
Marco TodescoDepartment of Botany, University of British Columbia, Vancouver, BC, Canada.
Loren H RiesebergDepartment of Botany, University of British Columbia, Vancouver, BC, Canada.
Gregory J BauteBreeding and Genetics Department, Aurora Cannabis, Inc., Comox, BC, Canada.
Jose M CeledonBreeding and Genetics Department, Aurora Cannabis, Inc., Comox, BC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Breeding genetic resistance to economically important crop diseases is the most sustainable strategy for disease management and enhancing agricultural and horticultural productivity, particularly where the application of synthetic pesticides is prohibited. Powdery mildew disease, caused by the biotrophic fungal pathogen Methods: In this study, we used bulked-segregant analysis combined with high-throughput RNA sequencing (BSRSeq) to identify and map a novel single dominant resistance (R) locus (designated PM2), that strongly suppresses powdery mildew infection and sporulation in Results and discussion: BSA mapped PM2 to chromosome 9. Histochemical analysis revealed that PM2-induced resistance is mediated by a highly localized hypersensitive response mainly in the epidermal cells of the host. Importantly, genetic markers capable of tracking PM2 resistance in breeding populations were developed using associated SNPs identified in this study. The ability to track PM2 will allow for successful introgression of PM resistance into elite cannabis cultivars and help move towards a more sustainable cannabis industry.

Indexed as

bulked-segregant analysisCannabis sativadisease resistancegenetic mappingmarker assisted selectionplant breedingpowdery mildewsustainable agriculture

Identifiers

PMID40182551
PMCPMC11966446

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.