Evidence map›Paper›PMID 40182516›Full record

ArticleFrontiers in public health2025

Associations between urinary glyphosate and arthritis: an US NHANES analysis.

Xiaoyao He, Liangyu Mi, Miaomiao Zhao, Yuli Ji, Yuting Hu, Yanan Gao, Lixia Qiu, Ke Xu

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoyao He *Department of Statistics, School of Public Health, Shanxi Medical University, Taiyuan, China.
Liangyu Mi *Department of Rheumatology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, China.
Miaomiao ZhaoDepartment of Rheumatology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, China.
Yuli JiDepartment of Rheumatology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, China.
Yuting HuDepartment of Rheumatology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, China.
Yanan GaoDepartment of Rheumatology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, China.
Lixia QiuDepartment of Statistics, School of Public Health, Shanxi Medical University, Taiyuan, China.
Ke XuDepartment of Rheumatology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: As the relationship between urine glyphosate and arthritis in adults in general is still unclear, the study set out to investigate it. Methods: A total of 1,689 people volunteered in the National Health and Nutrition Examination Surveys (US NHANES). Utilizing a multivariate logistic regression model to explore the association between urine glyphosate concentrations (both continuous with categorical) and the risks of developing arthritis, as well as the risks of various types of arthritis. Non-linear correlations have been investigated using restricted cubic spline and smooth curve fitting. We also conducted additional subgroup analyses using categorical defining features. Results: Patients with arthritis had urine glyphosate levels of 0.4 ng/mL, while non-arthritic individuals had levels of 0.3 ng/mL ( Conclusion: Increased exposure to urine glyphosate may be associated with an elevated risk of arthritis, particularly in the subgroup of osteoarthritis.

Indexed as

ArthritisGlycineHerbicidesAdultAgedFemaleGlyphosateHumansLogistic ModelsMaleMiddle AgedNutrition SurveysUnited StatesGlycineGlyphosateHerbicidesarthritiscross-sectional studylogistic regressionNHANESurinary glyphosate

Identifiers

PMID40182516
PMCPMC11965927

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.