Evidence map›Paper›PMID 40182316›Full record

ArticleNeurology. Clinical practice2025

Quality Improvement Initiative to Implement Anxiety Screening for Children and Teens With Headache and Epilepsy.

Christina Murphy, Sara E Molisani, Amanda C Riisen, Carinna M Scotti-Degnan, Dina Karvounides, Stephanie Witzman, Michael C Kaufman, Alexander K Gonzalez, Mark Ramos, Christina L Szperka and 2 more

Abstract read
In one paragraph

Article in Neurology. Clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Christina MurphySection of Pediatric Psychology, Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia.ORCID https://orcid.org/0000-0002-2049-4891
Sara E MolisaniDivision of Pediatric Neurology, Departments of Neurology and Pediatrics, Children's Hospital of Philadelphia and the University of Pennsylvania.ORCID https://orcid.org/0000-0001-7599-0668
Amanda C RiisenSection of Pediatric Psychology, Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia.ORCID https://orcid.org/0009-0004-8731-7517
Carinna M Scotti-DegnanSection of Pediatric Psychology, Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia.ORCID https://orcid.org/0009-0008-7066-903X
Dina KarvounidesSection of Pediatric Psychology, Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia.
Stephanie WitzmanDepartment of Digital and Technology Services, Children's Hospital of Philadelphia; and.ORCID https://orcid.org/0009-0007-8420-5079
Michael C KaufmanDepartment of Biomedical and Health Informatics, Translational Informatics Group, Children's Hospital of Philadelphia, PA.ORCID https://orcid.org/0000-0003-2718-296X
Alexander K GonzalezDepartment of Biomedical and Health Informatics, Translational Informatics Group, Children's Hospital of Philadelphia, PA.ORCID https://orcid.org/0000-0002-4402-398X
Mark RamosDepartment of Biomedical and Health Informatics, Translational Informatics Group, Children's Hospital of Philadelphia, PA.ORCID https://orcid.org/0009-0006-5765-6248
Christina L SzperkaDivision of Pediatric Neurology, Departments of Neurology and Pediatrics, Children's Hospital of Philadelphia and the University of Pennsylvania.ORCID https://orcid.org/0000-0003-4786-8889
Nicholas S AbendDivision of Pediatric Neurology, Departments of Neurology and Pediatrics, Children's Hospital of Philadelphia and the University of Pennsylvania.ORCID https://orcid.org/0000-0001-6166-2663
Division of Neurology Quality Improvement Program

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: We conducted a quality improvement initiative to implement standardized screening for anxiety among adolescents with headache and/or epilepsy receiving outpatient neurology care at a quaternary health care system, consistent with recommendations from the American Academy of Neurology. Our SMART (Specific, Measurable, Achievable, Relevant, and Time-Based) aim was to screen ≥90% of established patients aged 12 years or older seen by a participating health care professional using a standardized anxiety screener by February 2024. Methods: This initiative was conducted in patients seen for follow-up by 17 participating neurology health care professionals. Health care professional opinions were assessed before and after implementation of the Generalized Anxiety Disorder-7 (GAD-7), administered as a previsit questionnaire distributed using the electronic health record. The integrated workflow included a best practice advisory (BPA) alert that permitted easy access to interventions and automatic population of education materials into the after-visit summary. After 12 months of use (March 2023 to February 2024), we assessed demographic and diagnostic information, GAD-7 completion rates, anxiety symptom severity, BPA utilization, and health care professional acceptance of the intervention. Results: The GAD-7 was completed for 64% of 3,671 encounters and by 71% of 2031 unique patients. The GAD-7 was more often completed for encounters if the patient was female, younger, or White or had a headache diagnosis. Among unique patients, anxiety symptoms were minimal in 50%, mild in 24%, moderate in 17%, and severe in 10%. Severe anxiety symptoms were more often present in female patients or those with a headache diagnosis. Among patients with severe anxiety symptoms, 66% had established behavioral health care plans and, for remaining patients, referrals were made to community behavioral health care professionals (11%), or pediatric psychologists (4%) or social workers (3%) within neurology. Clinicians indicated that the approach was easy to use and improved the quality of patient care. Discussion: We implemented standardized EHR-based screening for anxiety symptoms for pediatric neurology patients, most of whom had headache or epilepsy. Screening was feasible, and approximately one-quarter of patients had moderate or severe anxiety symptoms. Future work will focus on improving completion rates of previsit questionnaires including the GAD-7 and optimizing clinician actions based on the screening data.

Identifiers

PMID40182316
PMCPMC11962050

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.