ArticlePlastic and reconstructive surgery. Global open2025
Biologic Response With and Without Acellular Dermal Matrix in Breast Reconstruction.
Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- ADM-Assisted Breast Reconstruction vs Micro-Polyurethane Foam-Covered Implants in the Prepectoral Space: A Monocentric Study.Aesthetic plastic surgery · 2026Article
- Capsule histology in breast reconstruction: different materials lead to different tissue responses - a case series.Frontiers in surgery · 2026Article
- Improving the Patient Experience in Breast Reconstruction: ERAS and Beyond.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Acellular dermal matrices (ADMs) are biologic meshes commonly used in implant-based breast reconstruction (IBBR) procedures to provide implant support and coverage. Although the etiology is not well understood, increasing preclinical and clinical evidence suggest that ADMs may help prevent capsular contracture, a frequent complication of IBBR, by modulating the inflammatory response in the tissue surrounding breast implants. The objective of this narrative review is to discuss the evidence supporting the role of inflammation in capsular contracture following IBBR without ADM, and to characterize the potential mechanism(s) by which ADMs may reduce the incidence of capsular contracture in IBBR. Methods: Relevant studies in English published up to December 31, 2023, were identified from 4 databases (BIOSIS Previews, Embase, MEDLINE, and Northern Light Life Sciences Conference Abstracts) using search terms such as "breast" and "capsular contracture." Results: This review discusses the potential factors (eg, expander-to-implant reconstruction, diminished collagen integrity, postmastectomy radiation therapy, surface of implant, plane of placement, incision type, hematoma, seroma, postoperative infection, and biofilm) and emerging biomarkers (eg, Conclusions: The studies summarized in this review suggest that ADMs may reduce the likelihood of capsular contracture in IBRR compared with no ADM use.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.