ArticleCureus2025
Symptomatic Common Carotid Artery Stenosis With a Persistent Primitive Hypoglossal Artery Presenting With Posterior Circulation Symptoms and Technical Challenges in Stenting.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Clinical importance of the persistent primitive hypoglossal artery in vascular lesions and endovascular treatment: a narrative review.Frontiers in surgery · 2026Review
- Persistent primitive hypoglossal artery: a classification-based approach to understanding and managing a rare vascular anomaly.Acta neurochirurgica · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The persistent primitive hypoglossal artery (PPHA) is a rare variant of the persistent carotid-vertebrobasilar anastomoses. When PPHA coexists with carotid artery stenoses, it typically presents ischemic symptoms of the anterior circulation. However, we report a unique case of common carotid artery (CCA) stenosis with PPHA presenting exclusively ischemic symptoms of the posterior circulation, which posed significant diagnostic challenges and required innovative modifications in embolic protection strategies during carotid artery stenting. A 65-year-old woman experienced recurrent bilateral ptosis, diplopia, and transient bilateral visual loss, suggestive of posterior circulation ischemia. Imaging revealed significant left CCA stenosis with a PPHA supplying the posterior circulation. Due to the large diameter of the CCA, standard distal protection was unfeasible. Instead, distal balloon protection was innovatively applied at the bifurcation of the PPHA and the internal carotid artery, where the slightly narrower diameter facilitated successful stenting. The postoperative course was favorable, with no recurrence of symptoms. PPHA-associated carotid stenosis can cause posterior circulation symptoms, complicating diagnosis. Understanding anatomical and hemodynamic variations like PPHA is crucial for effective treatment and ensuring optimal outcomes.
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Registered trials
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