Evidence map›Paper›PMID 40182156›Full record

ArticleJournal of rural medicine : JRM2025

Impact of heart rate on the outcome of hypothermic patients.

Soichiro Ota, Hiroki Nagasawa, Hiroaki Taniguchi, Tatsuro Sakai, Hiromichi Ohsaka, Kazuhiko Omori, Youichi Yanagawa

Abstract read
In one paragraph

Article in Journal of rural medicine : JRM, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Soichiro OtaDepartment of Acute Critical Care Medicine, Shizuoka Hospital, Juntendo University, Japan.
Hiroki NagasawaDepartment of Acute Critical Care Medicine, Shizuoka Hospital, Juntendo University, Japan.
Hiroaki TaniguchiDepartment of Acute Critical Care Medicine, Shizuoka Hospital, Juntendo University, Japan.
Tatsuro SakaiDepartment of Acute Critical Care Medicine, Shizuoka Hospital, Juntendo University, Japan.
Hiromichi OhsakaDepartment of Acute Critical Care Medicine, Shizuoka Hospital, Juntendo University, Japan.
Kazuhiko OmoriDepartment of Acute Critical Care Medicine, Shizuoka Hospital, Juntendo University, Japan.
Youichi YanagawaDepartment of Acute Critical Care Medicine, Shizuoka Hospital, Juntendo University, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to identify prognostic factors for hypothermia, including hormone levels. Materials and Methods: This retrospective analysis used data from our department's database from November 2018 to December 2023. Inclusion criteria comprised cases with a prehospital diagnosis of hypothermia (body temperature <35°C) established by emergency medical technicians. Patients in cardiac arrest upon arrival were excluded from the study. This study investigated various parameters, including age, sex, body temperature, systolic blood pressure, heart rate, Glasgow Coma Scale (GCS) score, and adrenocorticotropic hormone (ACTH), cortisol, thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4), C-reactive protein, total protein, albumin levels, and outcomes. Patients were categorized into two groups based on the discharge outcome: fatal and survival groups. This study compared the variables between the two groups. Results: There were 28 and 53 patients in the fatal and survival groups, respectively. The average heart rate and FT3 levels in the fatal group were significantly lower than those in the survival group. The average cortisol and CRP levels in the fatal group were significantly higher than those in the survival group. Conclusion: This is the first report to demonstrate that hypothermic patients with a fatal outcome tend to have low heart rate, low FT3 levels, high cortisol levels, and inflammation upon arrival at the hospital. Further studies with larger sample sizes are needed to confirm the clinical significance of our findings.

Indexed as

heart ratehypothermialow T3 syndrome

Identifiers

PMID40182156
PMCPMC11962193

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.