Evidence map›Paper›PMID 40182150›Full record

ArticleJournal of molecular and cellular cardiology plus2025

Rostafuroxin, the inhibitor of endogenous ouabain, ameliorates chronic undernutrition-induced hypertension, stroke volume, cardiac output, left-ventricular fibrosis and alterations in Na

Amaury Pereira-Acácio, João P M Veloso-Santos, Camile O Silva-Rodrigues, Debora Mello, Danilo S Alves-Bezerra, Glória Costa-Sarmento, Humberto Muzi-Filho, Carlla A Araújo-Silva, Jarlene A Lopes, Christina M Takiya and 2 more

Abstract read
In one paragraph

Article in Journal of molecular and cellular cardiology plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Amaury Pereira-AcácioGraduate Program of Translational Biomedicine, Grande Rio University/UNIGRANRIO, Duque de Caxias, Brazil.
João P M Veloso-SantosLeopoldo de Meis Institute of Medical Biochemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Camile O Silva-RodriguesGrande Rio University/UNIGRANRIO, Duque de Caxias, Brazil.
Debora MelloNational Center for Structural Biology and Bioimaging/CENABIO, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Danilo S Alves-BezerraGraduate Program of Translational Biomedicine, Grande Rio University/UNIGRANRIO, Duque de Caxias, Brazil.
Glória Costa-SarmentoCarlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Humberto Muzi-FilhoCarlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Carlla A Araújo-SilvaCarlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Jarlene A LopesCarlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Christina M TakiyaCarlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Sergian V CardozoGraduate Program of Translational Biomedicine, Grande Rio University/UNIGRANRIO, Duque de Caxias, Brazil.
Adalberto VieyraGraduate Program of Translational Biomedicine, Grande Rio University/UNIGRANRIO, Duque de Caxias, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our aim has been to investigate the effect of Rostafuroxin, an inhibitor of endogenous cardiotonic steroids (EO/CTS), on cardiac structure and function and cardiac Na

Indexed as

Cardiac sodium ATPasesChronic undernutritionEndogenous cardiotonic steroidsHypertensionRostafuroxin

Identifiers

PMID40182150
PMCPMC11967012

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.