Evidence map›Paper›PMID 40182026›Full record

ArticleFrontiers in oncology2025

Grading of clear cell renal cell carcinoma using diffusion MRI with a multimodal apparent diffusion model.

Shuang Wang, Tuo Ji, Dan Yu, Yimeng Dai, Butian Zhang, Lin Liu

Abstract read
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Shuang WangDepartment of Radiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.
Tuo JiUrology Department 1st Inpatient Area, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.
Dan YuDepartment of MR Research Collaboration, United Imaging Research Institute of Intelligent Imaging, Beijing, China.
Yimeng DaiDepartment of Radiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.
Butian ZhangDepartment of Radiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.
Lin LiuDepartment of Radiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess the feasibility of utilizing parameters derived from a multimodal apparent diffusion (MAD) model to distinguish between low- and high-grade clear cell renal cell carcinoma (ccRCC). Method: Diffusion-weighted imaging (DWI) scans with 12 b-values (0 - 3000 s/mm²) were conducted on 54 patients diagnosed with ccRCC (30 low-grade and 24 high-grade). The MAD model parameters, including diffusion coefficients (D Result: Significant differences between low- and high-grade ccRCC were observed in D Conclusion: The MAD diffusion model shows promise as a non-invasive imaging tool for distinguishing between low- and high-grade ccRCC, which may aid in preoperative planning and personalized treatment strategies.

Indexed as

clear cell renal cell carcinomadiffusion-weighted imagingmagnetic resonance imagingmultimodal apparent diffusion modelWorld Health Organization/international society of urological pathology grading system

Identifiers

PMID40182026
PMCPMC11965134

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.