Evidence map›Paper›PMID 40182000›Full record

ArticleFrontiers in pediatrics2025

Urinary biomarkers improve prediction of AKI in pediatric cardiac surgery.

Oscar T Deal, Thomas Mitchell, Amy G Harris, Kelly Saunders, Julie Madden, Carrie Cherrington, Karen Sheehan, Mai Baquedano, Rusununguko Kanyongo, Giulia Parolari and 4 more

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Research progress on biomarkers for acute kidney injury in children.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Oscar T DealBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, United Kingdom.
Thomas MitchellBristol Heart Institute, University Hospital Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom.
Amy G HarrisBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, United Kingdom.
Kelly SaundersBristol Heart Institute, University Hospital Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom.
Julie MaddenBristol Heart Institute, University Hospital Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom.
Carrie CherringtonBristol Heart Institute, University Hospital Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom.
Karen SheehanBristol Heart Institute, University Hospital Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom.
Mai BaquedanoBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, United Kingdom.
Rusununguko KanyongoCardiovascular Research Unit, University of Cape Town, Cape Town, South Africa.
Giulia ParolariBristol Heart Institute, University Hospital Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom.
Kirsty PhillipsBristol Heart Institute, University Hospital Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom.
Serban StoicaBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, United Kingdom.
Massimo CaputoBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, United Kingdom.
Francesca Bartoli-LeonardBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, United Kingdom.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Acute kidney injury (AKI) is a common postoperative complication of paediatric congenital heart disease (CHD) surgery, associated with increased morbidity and mortality. Current diagnostic approaches are unreliable in the early postoperative period, delaying diagnosis and treatment. This study investigates the efficacy of inflammatory and renal biomarkers in the early detection of postoperative AKI in paediatric CHD surgery patients. Biomarkers were assessed in urine and serum samples collected pre- and 24 h postoperatively from paediatric patients (median age 27 weeks) undergoing corrective CHD surgery (

Indexed as

acute kidney injurybiomarkercardiac surgerycongential heart diseaseneonatalpaediatric surgery

Identifiers

PMID40182000
PMCPMC11965893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.