ArticleFrontiers in nutrition2025
Temporal trends of ischemic stroke attributable to diet high in sodium in China from the global burden of disease study 2021.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed.
- Ischemic Stroke Burden in China and Other G20 Nations (1990-2021): A Comparative Analysis From the Global Burden of Disease Study 2021 and Trend Projections Through 2031.Health care science · 2026Article
- Trends and projections of IHD burden attributable to dietary high sodium and kidney dysfunction in G20 countries, 1990-2050.PloS one · 2026Article
- Association between red blood cell distribution width to albumin ratio and pneumonia risk in acute ischemic stroke: evidence from two independent cohorts.Frontiers in nutrition · 2026Article
- Nutritional risk, cold exposure, and stroke severity in older adults: an exploratory analysis of the "collapsed furnace" hypothesis.Frontiers in public health · 2026Article
- The burden of ischemic stroke and its attributable risk factors among people aged 15-49 years in Asia, 1990-2021: results from the global burden of disease study 2021.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Trend and burden of ischemic stroke attributable to high body mass index in China from 1990 to 2021, with projection to 2044.PloS one · 2025Article
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7 authors.
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Abstract
Background: Ischemic stroke is a significant global health burden, with high sodium intake recognized as a key risk factor. This study aimed to assess the disease burden of ischemic stroke attributable to diet high in sodium in China from 1990 to 2021. Additionally, we analyzed the influence of age, period, and cohort effects on the trends in ischemic stroke burden and projected the disease burden from 2022 to 2036. Methods: Data from the Global Burden of Disease Study 2021 (GBD 2021) were used to analyze the ischemic stroke burden among high-risk populations in China. Annual average percent change (AAPC) was calculated using Joinpoint regression models to evaluate trends in ischemic stroke burden from 1990 to 2021. Age-period-cohort models were employed to estimate the independent effects of age, period, and cohort on the ischemic stroke burden, and to project the burden from 2022 to 2036 using Bayesian age-period-cohort models. Results: From 1990 to 2021, ischemic stroke mortality attributable to diet high in sodium in China showed a continuous increase, while the age-standardized mortality and disability-adjusted life years (DALYs) significantly declined. In the age-period-cohort analysis, the age effect on ischemic stroke burden increased steadily over the study period. Period effects revealed an initial decline in the relative risk (RR) of ischemic stroke mortality and DALY rates, followed by an increase in cohorts born before 2004-2009, and a gradual decline in cohorts born after that period. Cohort effects demonstrated a continuous decline in the relative risk of ischemic stroke mortality and DALY rates from 1990 to 2021. Conclusion: This study found that ischemic stroke attributable to a diet high in sodium in China fluctuated from 1990 to 2021, with a declining trend observed in recent years. Projections indicate that this downward trend will continue. Age and birth period are key factors influencing the disease burden, with older adults and men being particularly affected. Future policy efforts should focus on enhancing health management in high-risk populations to further reduce the burden of ischemic stroke linked to high sodium intake.
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