Evidence map›Paper›PMID 40181944›Full record

SynthesisFrontiers in nutrition2025

Impact of anti-inflammatory diets on cardiovascular disease risk factors: a systematic review and meta-analysis.

Ruixue Jiang, Ting Wang, Kunlin Han, Peiqiang Peng, Gaoning Zhang, Hanyu Wang, Lijing Zhao, Hang Liang, Xuejiao Lv, Yanwei Du

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Trial
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ruixue JiangDepartment of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Ting WangDepartment of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Kunlin HanDepartment of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Peiqiang PengDepartment of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Gaoning ZhangDepartment of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Hanyu WangDepartment of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Lijing ZhaoDepartment of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin Province, China.
Hang LiangDepartment of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin Province, China.
Xuejiao LvDepartment of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Yanwei DuDepartment of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chronic inflammation, via multiple pathways, influences blood pressure and lipid profiles, serving as a significant risk factor for the onset of cardiovascular disease (CVD). Anti-inflammatory dietary patterns may ameliorate CVD risk factors through the modulation of inflammatory mediators and metabolic factors, potentially leading to improved cardiovascular outcomes. Current findings regarding the relationship between dietary habits and CVD risk factors, such as blood pressure and lipid levels, exhibit considerable variability. We performed a comprehensive systematic review and meta-analysis to explore the possible association between anti-inflammatory dietary patterns (such as the Mediterranean diet, DASH diet, Nordic diet, Ketogenic diet, and Vegetarian diet) and CVD risk factors. Methods: We conducted a comprehensive search across five databases: PubMed, Web of Science, Cochrane Library, Embase, and China National Knowledge Infrastructure (CNKI). Ultimately, we identified 18 eligible randomized controlled trials (including randomized crossover trials), which were subjected to meta-analysis utilizing RevMan 5 and Stata 18. Results: A comprehensive meta-analysis of these studies conducted based on random effects model indicated that, in comparison to an Omnivorous diet, interventions centered on anti-inflammatory diets were linked to significant reductions in Systolic Blood Pressure (SBP) (MD: -3.99, 95% CI: -6.01 to -1.97; Discussion: The findings indicate that anti-inflammatory diets may lower serum hs-CRP levels and positively influence the reduction of CVD risk factors, such as blood pressure and lipid profiles, thereby contributing to the prevention and progression of cardiovascular conditions. Most of the outcome indicators had low heterogeneity; sensitivity analyses were subsequently conducted on outcome measures demonstrating substantial heterogeneity, revealing that the findings remained consistent.

Indexed as

anti-inflammatory dietsblood pressurecardiovascular disease risk factorshs-CRPlipidsmeta-analysis

Identifiers

PMID40181944
PMCPMC11965126

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.