Evidence map›Paper›PMID 40181935›Full record

ArticleFrontiers in sports and active living2025

Autonomic modulation and skeletal muscle oxygenation with intermittent low-load blood flow restriction knee extension.

Andrew R Garner, Jacob D Fanno, Ryan McGrath, Jacob Erickson, Kyle J Hackney

Abstract read
In one paragraph

Article in Frontiers in sports and active living, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrew R GarnerDepartment of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, United States.
Jacob D FannoDepartment of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, United States.
Ryan McGrathDepartment of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, United States.
Jacob EricksonDepartment of Human Performance, Sport, and Health, Bemidji State University, Bemidji, MN, United States.
Kyle J HackneyDepartment of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This investigation determined if an acute bout of low-load knee extension (KE) with intermittent blood flow restriction (BFR) influenced autonomic modulation and skeletal muscle oxygenation (SmO Methods: Fourteen physically active males completed three different sessions: one-repetition maximum (1RM), KE with BFR (BFR-KE) at 20% 1RM (cuff pressure=143 ± 13 mmHg), and KE with free blood flow at 20% 1RM (Control-KE). Heart rate variability (HRV) metrics: logarithmically transformed (ln) square root of the mean differences of successive R-R intervals (lnRMSSD), high frequency power (lnHF), and low frequency power (lnLF), as well as SmO Results: From baseline to 15 min post-exercise lnRMSSD decreased in both BFR-KE and Control-KE (4.34 ± 0.43-3.75 ± 0.82 ms, Conclusion: Unilateral BFR exercise with individualized cuff pressure and intermittent application facilitated greater localized muscular stress and perceptual effort, but there was no influence of vascular occlusion on post-exercise autonomic modulation compared to volume-matched exercise with free blood flow.

Indexed as

autonomic modulationblood flow restrictionheart rate variabilityresistance exerciseskeletal muscle oxygenation

Identifiers

PMID40181935
PMCPMC11966393

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.