ArticleIndian journal of psychiatry2025
Does HCV treatment completion affect the neurocognitive outcomes in patients on opioid agonist maintenance treatment: A secondary analysis.
Article in Indian journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Aim: This secondary analysis investigated whether completing Direct-Acting Antiviral (DAA) treatment affects neurocognitive outcomes in patients with opioid use disorder (OUD) undergoing opioid agonist maintenance treatment (OAMT). Methods: Data from 45 participants (22 DAA treatment completers and 23 non-completers) were analyzed. Neurocognitive function was assessed at baseline and six months using the Wisconsin Card Sorting Test (WCST), Trail Making Tests (TMT A and B), Visual and Verbal N-Back tests, and Iowa Gambling Task (IGT). Results: General Linear Model (GLM) analysis revealed significant improvements in cognitive function over time in both groups, with notable gains in WCST total correct responses ( Conclusion: These findings highlight that even incomplete DAA treatment, alongside OAMT, yields significant cognitive benefits, underscoring the importance of integrated care.
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