ArticleIndian journal of endocrinology and metabolism
Prospective Validation of Accuracy of American College of Radiologists- Thyroid Imaging Reporting and Data System (ACR-TIRADS) in Diagnosing Malignancy in Thyroid Nodule and a Prediction Score (TiPS) for Thyroid Malignancy.
Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Studies on diagnostic accuracy of revised ACR-TIRADS have been mostly retrospective and includes selection bias for surgery. Methods: Consecutive subjects >12 years of age, with palpable or ultrasound-revealed thyroid nodule, were included in the study. Nodules of size >1 cm or TIRADS score 4 or 5 >5 mm underwent ultrasound-guided FNAC. All Bethesda 4, 5 and 6 nodules underwent thyroidectomy. Patients with Bethesda 3 nodules were given options of close follow up or surgery. Results: There were 253 benign (Bethesda 2), 23 malignant (Bethesda 6) and 41 indeterminate (Bethesda 3,4,5) nodules. Among 41 indeterminate nodules, 19 underwent surgery of which 14 were malignant. 295 nodules had a definitive outcome (defined as final outcome variable); which could be a benign cytology report or a histopathology report. Proportion of thyroid cancer was 12.5%. ACR-TIRADS had a sensitivity of 100% and specificity of 60.5%, considering final outcome variable as gold standard and ACR-TIRADS 1-3 as test negative and score 4-5 positive. Lower age and higher serum TSH level were associated with malignancy ( Conclusion: Owing to high sensitivity, ACR-TIRADS can be considered as a good tool to rule-out malignancy, but not to predict the same due to lower specificity. Cumulative scoring system had high diagnostic accuracy for prediction of malignancy risk and can be a useful tool for selecting nodules for surgery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.