ArticleInternational journal of nanomedicine2025
Dynamic Covalent Bond-Based Nanoassembly of Curcumin to Enhance the Selective Photothermal Therapy for Tumor Treatment.
Article in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- SMart Nanoparticle-Hydrogel Hybrid System for Synergistic Eradication of Infection and Promotion of Wound Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- From Barrier to Gateway: Nanomaterials Reshaping the Tumor Microenvironment for Therapy.International journal of nanomedicine · 2026Review
Corrections and comments
- Erratum issued
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Owing to the uneven distribution of photothermal agents (PTAs), photothermal therapy (PTT) can damage normal tissues. The dynamic reversible covalent bond, which can significantly improve the oxidation stability of the drug and the characteristics of responsive drug release, thus improving the conversion efficiency of the drug, is a feasible solution to enhance the selective PTT for tumor treatment. Methods: The nanoassembly loaded curcumin (Cur) with dynamic covalent boronate and encapsulated Indocyanine Green (ICG) in the phospholipid bilayer by dynamic self-assembly. Results: The pH-responsive dynamic covalent bond-based nanoassembly system has great selective release of drugs in the tumor microenvironment and photothermal conversion efficiency. Furthermore, LIP-C/I could increase the antitumor effect through the combination of PTT and chemotherapy (CT). The experiments in vitro and in vivo have demonstrated that LIP-C/I could enhance selective PTT for tumor treatment. Discussion: Our nanoassembly system provides an alternative approach for enhancing selective PTT for tumor treatment using dynamic covalent boronate.
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Registered trials
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