ArticleAPL bioengineering2025
Fluorescence spectroscopy as a novel tool in hematological diagnostics.
Article in APL bioengineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Application Value of Blood Routine-Derived Indices for the Evaluation of Disease Activity in Systemic Lupus Erythematosus.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present paper explores the application of fluorescence spectroscopy in erythrocyte analysis, aiming to enhance spectral diagnostics in biomedical research. The primary objective is to develop innovative methodologies for improving the precision of hematological diagnostics and disease monitoring. Utilizing 3D fluorescence spectroscopy and excitation/emission wavelength mapping, erythrocyte samples are examined across multiple wavelengths, generating distinct spectral profiles that reveal biochemical composition, oxygenation status, and metabolic alterations. Advanced data analysis enables the identification of pathological changes in erythrocytes, contributing to a more comprehensive diagnostic approach. Additionally, this study integrates fluorescence spectroscopy with traditional clinical hematological analysis, comparing spectroscopic findings with complete blood count parameters for two patients. Blood samples were subjected to fluorescence analysis under deuterium, halogen, and ultraviolet excitation sources, allowing for a detailed correlation between spectroscopic biomarkers (hemoglobin, deoxyhemoglobin, and plasma characteristics) and clinical parameters (hemoglobin concentration, hematocrit, and red blood cell indices). The findings demonstrate that fluorescence spectroscopy provides complementary diagnostic insights, detecting subtle physiological variations in blood composition that conventional methods might overlook. By integrating these two diagnostic approaches, this research highlights the potential of fluorescence-based techniques as a noninvasive and efficient tool for hematological diagnostics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.