Evidence map›Paper›PMID 40181510›Full record

ArticleThe Plant journal : for cell and molecular biology2025

The homeostasis of β-alanine is key for Arabidopsis reproductive growth and development.

Si Wu, Youjun Zhang, Urszula Luzarowska, Lei Yang, Mohamed A Salem, Venkatesh P Thirumalaikumar, Nir Sade, Vadim E Galperin, Alisdair Fernie, Arun Sampathkumar and 3 more

Abstract read
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In one paragraph

Article in The Plant journal : for cell and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Si WuDepartment of Life Sciences, Ben Gurion University of the Negev, Beersheva, Israel.
Youjun ZhangMax Planck Institute of Molecular Plant Physiology, Am Mühlenberg, Potsdam-Golm, 114476, Germany.
Urszula LuzarowskaDepartment of Life Sciences, Ben Gurion University of the Negev, Beersheva, Israel.
Lei YangMax Planck Institute of Molecular Plant Physiology, Am Mühlenberg, Potsdam-Golm, 114476, Germany.
Mohamed A SalemMax Planck Institute of Molecular Plant Physiology, Am Mühlenberg, Potsdam-Golm, 114476, Germany.ORCID 0000-0003-0332-3860
Venkatesh P ThirumalaikumarPurdue Proteomics Facility, Bindley Biosciences, Purdue University, West Lafayette, Indiana, 47907, USA.
Nir SadeSchool of Plant Sciences and Food Security, Institute for Cereal Crops Research, Tel Aviv University, Tel Aviv, 69978, Israel.
Vadim E GalperinBLAVATNIK CENTER for Drug Discovery, Tel Aviv University, Tel Aviv, 69978, Israel.
Alisdair FernieMax Planck Institute of Molecular Plant Physiology, Am Mühlenberg, Potsdam-Golm, 114476, Germany.ORCID 0000-0001-9000-335X
Arun SampathkumarMax Planck Institute of Molecular Plant Physiology, Am Mühlenberg, Potsdam-Golm, 114476, Germany.ORCID 0000-0003-1703-0137
Shimon BershteinDepartment of Life Sciences, Ben Gurion University of the Negev, Beersheva, Israel.
Corina M FusariCentro de Estudios Fotosintéticos y Bioquímicos (CEFOBI-CONICET-UNR), Suipacha 570, Rosario, S2000LRJ, Argentina.ORCID 0000-0001-6809-0266
Yariv BrotmanSchool of Plant Sciences and Food Security, Institute for Cereal Crops Research, Tel Aviv University, Tel Aviv, 69978, Israel.

Funding

Consejo Nacional de Investigaciones Científicas y TécnicasIsrael Science Foundation 859/19Max-Planck-Gesellschaft
6 · The paper itself

Abstract

β-Alanine, an abundant non-proteinogenic amino acid, acts as a precursor for coenzyme A and plays a role in various stress responses. However, a comprehensive understanding of its metabolism in plants remains incomplete. Previous metabolic genome-wide association studies (mGWAS) identified ALANINE:GLYOXYLATE AMINOTRANSFERASE2 (AGT2, AT4G39660) linked to β-alanine levels in Arabidopsis under normal conditions. In this study, we aimed to deepen our insights into β-alanine regulation by conducting mGWAS under two contrasting environmental conditions: control (12 h photoperiod, 21°C, 150 μmol m

Indexed as

Arabidopsisbeta-AlanineArabidopsis ProteinsGene Expression Regulation, PlantGenome-Wide Association StudyHomeostasisQuantitative Trait LociStress, PhysiologicalTransaminasesArabidopsis Proteinsbeta-AlanineTransaminasesAGT2ALDH6B2metabolic genome‐wide association studiesmetabolic regulationplant developmentseed abortionyield traitsβ‐alanine

Identifiers

PMID40181510
PMCPMC11969031

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.