Evidence map›Paper›PMID 40181483›Full record

ArticleBMC psychology2025

What factors influence thriving in adolescent and young adult cancer patients? A focus on psychological health, biological markers, and quality of life.

Yi Zhou, Yinglong Duan, Jian Zhou, Qinqin Cheng, Ning Qin, Xing Zhou, Yuxuan Li, Juan Luo, Huiyi Zhang, Jiayi Zhu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yi ZhouNursing Department, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Yinglong DuanNursing Department, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Jian ZhouCollege of Mechanical and Vehicle Engineering, Hunan University, Changsha, Hunan, China.
Qinqin ChengHunan Cancer Hospital, Changsha, Hunan, China.
Ning QinXiangya School of Nursing, Central South University, Changsha, Hunan, China.
Xing ZhouXiangya School of Nursing, Central South University, Changsha, Hunan, China.
Yuxuan LiXiangya School of Nursing, Central South University, Changsha, Hunan, China.
Juan LuoXiangya School of Nursing, Central South University, Changsha, Hunan, China.
Huiyi ZhangXiangya School of Nursing, Central South University, Changsha, Hunan, China.
Jiayi ZhuXiangya School of Nursing, Central South University, Changsha, Hunan, China.
Jianfei XieNursing Department, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China. xiejianfei@csu.edu.cn.
Andy S K ChengSchool of Health Sciences, Western Sydney University, Sydney, Australia.

Funding

National Natural Science Foundation of China 82073409Wisdom Accumulation and Talent Cultivation Project of the Third Xiangya Hospital of Central South University BJ202205
6 · The paper itself

Abstract

purposeThis study explores the role of psychological health, biological markers, and quality of life (QoL) in influencing thriving - defined as resilience and enhanced well-being - among adolescent and young adult (AYA) cancer patients.

methodsA total of 148 AYA cancer patients were assessed for psychological health indicators (anxiety, depression, character strengths), physiological markers (cortisol awakening response [CAR], melatonin), and QoL. Thriving levels were evaluated using ordinary least squares regression and quantile regression to identify predictors across different thriving percentiles.

resultsPsychological health was the strongest predictor of thriving. Depression negatively impacted thriving at lower levels, while inquisitiveness consistently enhanced it. CAR and melatonin played roles at higher and median thriving levels, respectively, and QoL was most influential at lower levels. These factors collectively explained 23.0% of the variance in thriving scores.

conclusionsThis study highlights depression, inquisitiveness, CAR, and QoL as key factors influencing thriving in AYA cancer patients. Depression affects thriving at lower levels, inquisitiveness enhances thriving consistently, CAR is significant at higher levels, and QoL is crucial at lower levels. These findings underscore the need for tailored interventions to support thriving across varying levels of adaptation.

Indexed as

Mental HealthNeoplasmsQuality of LifeResilience, PsychologicalAdaptation, PsychologicalAdolescentAdultAnxietyBiomarkersDepressionFemaleHumansHydrocortisoneMaleMelatoninYoung AdultBiomarkersHydrocortisoneMelatoninAdolescent and young adultBiomarkerPsychological healthQuality of lifeThriving

Identifiers

PMID40181483
PMCPMC11969851

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.