SynthesisBMC musculoskeletal disorders2025
Acute compartment syndrome in tibial fractures: a meta-analysis.
Synthesis in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Trends and Associated Factors of Pediatric Acute Compartment Syndrome From 2015 to 2024: A Large, Retrospective Cohort Analysis.Journal of the Pediatric Orthopaedic Society of North America · 2026Article
- Biomechanical evaluation of X-ray permeable CF/PEEK composite versus conventional titanium alloy for tibial external fixation plates: a finite element analysis.Scientific reports · 2026Article
- Epidemiology and outcomes of tibial plateau fractures involving the medial plateau : a comparative analysis of AO type B and C injuries.Bone & joint open · 2026Article
- Ultrasonography of the Fasciae and Common Pathologies: The Game Changer.Diagnostics (Basel, Switzerland) · 2025Review
- Finite Element Analysis of Von Mises Stress in External Fixators for Open Tibial Fractures: A Comparative Study of ASTM F1541-02 and Tibia-Based Models in Indonesian Patients.Healthcare technology lettersArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAcute compartment syndrome (ACS) is a severe complication associated with tibial fractures, which can result in irreversible muscle and nerve damage if not promptly identified and treated.
methodThis study systematically searched PubMed, EMBASE, the Cochrane Library, and Web of Science. Data on demographics, fracture attributes, injury mechanisms, and biomarkers were extracted. Meta-analyses were performed using both fixed- and random-effects models, depending on the degree of heterogeneity.
resultA total of 17 studies were included. Younger adult age and older age in pediatric populations were both linked to higher ACS risk, depending on the age group. ale sex was strongly associated with ACS. High-energy traumaand polytrauma were also associated with a heightened risk. Delayed external fixation also showed a protective effect, albeit based on limited evidence. Biomarkers, including elevated monocyte count and creatine kinase-MB levels, were also significant predictors.
conclusionYounger adult age, male sex, high-energy trauma, and polytrauma were identified as critical risk factors for ACS in tibial fractures. Findings emphasize the need for standardized definitions and prospective investigations. Further research addressing pediatric age ranges, fracture location, and biomarker validation is essential to refine risk assessment and optimize early interventions.
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