SynthesisBMC pregnancy and childbirth2025
Efficacy of skin-to-skin contact between mother and newborn during the third stage of labour in reducing postpartum haemorrhage risk.
Synthesis in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the efficacy of skin-to-skin contact (SSC) in reducing the risk of postpartum haemorrhage and blood loss after childbirth.
backgroundPostpartum haemorrhage is a leading cause of preventable mortality, particularly in developing countries. Although various strategies exist for its prevention, the effect of SSC remains unclear.
designSystematic review with meta-analysis. DATA SOURCES: Searches were conducted in PubMed, Scopus, Cochrane Library, CINAHL, Google Scholar, and Web of Science up to May 2024. REVIEW
methodsThe PRISMA guidelines were followed. Prospective clinical trials were included and assessed using the revised Cochrane RoB 2 tool for randomized controlled trials and ROBINS-I for non-randomized studies. The meta-analysis was performed using STATA 18.
resultsThe analysis of 18 prospective clinical trials showed that SSC during the third stage of labour was associated with a reduction in the incidence of uterine atony and a lower likelihood of blood loss greater than or equal to 500 mL. Additionally, SSC was linked to a decrease in mean blood loss during the third stage of labour, the first two hours postpartum, and at 24 h postpartum. No significant differences were found in the incidence of severe postpartum haemorrhage.
conclusionsSSC during the third stage of labour appears to be effective in reducing the risk of uterine atony, blood loss of 500 mL or more, and mean postpartum blood loss. This suggests significant potential for improving obstetric outcomes. However, given the high risk of bias in the studies analysed, caution is required in interpreting these results. Further high-quality research is needed to confirm these benefits, particularly in caesarean sections. IMPACT: Postpartum haemorrhage is one of the leading causes of maternal mortality, particularly in developing countries. This meta-analysis suggests that SSC during the third stage of labour could be a key intervention in reducing the risk of uterine atony, blood loss of 500 mL or more, and mean postpartum blood loss. These findings are especially relevant in countries where access to uterotonic drugs is limited, highlighting the need for cost-effective, evidence-based alternatives to improve maternal health. PATIENT OR PUBLIC CONTRIBUTION: No patient or public contribution.
trial registrationPROSPERO registration number CRD 42024543192.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.