ArticleBMC plant biology2025
Transcriptome profiling reveals the mechanism of fruit navel development in melon (Cucumis melo L.).
Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundMelon is an important horticultural crop cultivated extensively worldwide. The size of the fruit navel, the terminal region of melon fruits, significantly influences the appearance quality of the fruit. However, the regulatory factors and molecular mechanisms governing the fruit navel development remain poorly understood in melon.
resultsIn this study, the regulators and mechanisms underlying fruit navel development were investigated through phenotypic analysis, RNA sequencing (RNA-seq) and RT-qPCR methods. The inbred line 'T03' and a big fruit navel mutant 'BFN' of melon were used as experimental materials. RNA-seq analysis identified 116 differentially expressed genes (DEGs), including 54 up-regulated and 62 down-regulated genes, in both the green bud (GB) and ovary at anthesis (OA) stages of the 'BFN' melon compared to the 'T03' melon. Functional enrichment analysis revealed that these 116 DEGs were significantly associated with "Sesquiterpenoid and triterpenoid biosynthesis", "Circadian rhythm-plant", "Galactose metabolism" and "Biosynthesis of various alkaloids" pathways. There were three (AP2/ERF, MYB and C2H2 types) and eight (AP2/ERF, MADS-box, homeobox domain and bZIP types) transcription factors presented in up-regulated and down-regulated DEGs, and their putative target genes were predicted. Based on KEGG and expression analyses, two terpene cyclase/mutase genes (MELO3 C001812 and MELO3 C004329) were identified as being involved in the "Sesquiterpenoid and triterpenoid biosynthesis" pathway, and their transcripts were significantly downregulated in all detected development stages (EGB, GB, GYB, YB and OA) of 'BFN' fruits compared with 'T03' fruits.
conclusionsThe findings of this study elucidate a fundamental regulatory mechanism underlying fruit navel formation, and identify two key negative regulators, MELO3C001812 and MELO3C004329, involved in the development of the fruit navel in melon.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.