Evidence map›Paper›PMID 40181263›Full record

ArticleBMC pregnancy and childbirth2025

Prediction of clinical pregnancy after frozen embryo transfer based on ultrasound radiomics: an analysis based on the optimal periendometrial zone.

Fangfang Xu, Ying Zhang, Qianqing Ma, Lili Hu, Yu Li, Chuanfen Gao, Peipei Guo, Xianyue Yang, Yi Zhou, Jie Zhang and 2 more

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fangfang Xu *Department of Ultrasound, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei, Anhui, 230022, People's Republic of China.
Ying Zhang *Hefei Maternal and Child Health Hospital, Hefei, China.
Qianqing Ma *Department of Ultrasound, Yijishan Hospital, the First Affiliated Hospital of Wannan Medical College, Wuhu, China.
Lili HuDepartment of Ultrasound, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei, Anhui, 230022, People's Republic of China.
Yu LiDepartment of Ultrasound, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei, Anhui, 230022, People's Republic of China.
Chuanfen GaoDepartment of Ultrasound, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei, Anhui, 230022, People's Republic of China.
Peipei GuoCenter for Reproductive Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Xianyue YangDepartment of Ultrasound, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei, Anhui, 230022, People's Republic of China.
Yi ZhouDepartment of Ultrasound, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei, Anhui, 230022, People's Republic of China.
Jie ZhangInformation Center, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Heng WangInstitute of Health Big Data and Population Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China. wangheng1969@163.com.
Chaoxue ZhangDepartment of Ultrasound, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei, Anhui, 230022, People's Republic of China. zcxay@163.com.

Funding

Clinical Research Foundation Project of Anhui Medical University 2022xkj167Research Funds of Center for BigData and Population Health of IHM. JKS2022002the Research fund Project of Anhui institude of Translational Medicine 2021zhyx-C35
6 · The paper itself

Abstract

backgroundTo investigate the optimal periendometrial zone (PEZ) in ultrasound (US) images and assess the performance of ultrasound radiomics in predicting the outcome of frozen embryo transfer (FET).

methodsThis prospective study had 422 female participants (training set: n = 358, external validation set: n = 64). We delineated the region of interest (ROI) of the endometrium (EN) from ultrasound images of the median sagittal surface of the uteri of patients. We determined the ROIs of PEZ on US images by automatically expanding 2.0, 4.0, 6.0, and 8.0 mm radii surrounding the EN. We determined the radiomics characteristics based on the ROIs of the endometrium and PEZ, then compared the different sizes of PEZ to determine the optimal PEZ. We constructed models of the EN and optimal PEZ using six machine learning algorithms. We developed a combined model using the radiomics characteristics of EN and the optimal PEZ. We evaluated the performance of the three models using the area under the curve (AUC).

resultsThe optimal PEZ was 4.0 mm with a maximum AUC of 0.715 (95% confidence interval (CI): 0.581 - 0.833) in the external validation set. The combined radiomics model (endometrium and PEZ

conclusionsPEZ

Indexed as

Embryo TransferEndometriumAdultCryopreservationFemaleHumansPredictive Value of TestsPregnancyPregnancy RateProspective StudiesRadiomicsUltrasonographyEndometrial ReceptivityFrozen-embryo transferRadiomicsUltrasound

Identifiers

PMID40181263
PMCPMC11970006

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.