Evidence map›Paper›PMID 40181134›Full record

ArticleCommunications biology2025

Neurocognitive mechanisms underlying action tool knowledge tasks: specificity of tool-tool compared to hand-tool compatibility tasks.

Mathieu Lesourd, François Osiurak, Julie Martin, Sébastien Hague, Margolise Laroze, Gautier Clément, Elisabeth Medeiros de Bustos, Guillaume Fargeix, Eloi Magnin, Thierry Moulin

Registry-linked trialAbstract read
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03555162 (Cerebral Bases of Tool Use and Tool Evolution), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03555162 nacompletednot on this map

Cerebral Bases of Tool Use and Tool Evolution

TypeinterventionalSponsorHospices Civils de LyonRan2018 to 2019Enrolled70ConditionsHealthyArmsfMRI
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mathieu LesourdUniversité Marie et Louis Pasteur, INSERM, UMR 1322 LINC, F-25000, Besançon, France. mathieu.lesourd@univ-fcomte.fr.ORCID http://orcid.org/0000-0002-1011-3047
François OsiurakLaboratoire d'Étude des Mécanismes Cognitifs (EA 3082), Université Lyon 2, Bron, France.ORCID http://orcid.org/0000-0003-3449-6377
Julie MartinUnité de Neurologie Vasculaire (UNV) et Hôpital de jour (HDJ), Service de Neurologie, CHRU de Besançon, Besançon, France.
Sébastien HagueUnité de Neurologie Vasculaire (UNV) et Hôpital de jour (HDJ), Service de Neurologie, CHRU de Besançon, Besançon, France.
Margolise LarozeUnité de Neurologie Vasculaire (UNV) et Hôpital de jour (HDJ), Service de Neurologie, CHRU de Besançon, Besançon, France.
Gautier ClémentCentre Mémoire Ressources et Recherche (CMRR), service de Neurologie, CHRU Besançon, F-25000, Besançon, France.
Elisabeth Medeiros de BustosUniversité Marie et Louis Pasteur, INSERM, UMR 1322 LINC, F-25000, Besançon, France.
Guillaume FargeixUnité de Neurologie Vasculaire (UNV) et Hôpital de jour (HDJ), Service de Neurologie, CHRU de Besançon, Besançon, France.
Eloi MagninUniversité Marie et Louis Pasteur, INSERM, UMR 1322 LINC, F-25000, Besançon, France.
Thierry MoulinUniversité Marie et Louis Pasteur, INSERM, UMR 1322 LINC, F-25000, Besançon, France.

Funding

Agence Nationale de la Recherche (French National Research Agency) ANR-21-CE28-0023-01
6 · The paper itself

Abstract

Action tool knowledge can be assessed mainly with two kinds of tasks: tool-tool and hand-tool compatibility tasks. While these tasks are used to assess action tool knowledge, recent data showed striking dissociations between these tasks in brain-damaged patients. In this study, we explored the neuropsychological dissociations (Experiment 1; 60 brain-damaged patients) and the potential cognitive mechanisms engaged during these two tasks (Experiment 2; 52 healthy participants). Finally, we also reanalyzed fMRI data to investigate the neural bases engaged in tool-tool and hand-tool compatibility tasks (Experiment 3; 34 healthy participants). The three experiments provide convergent arguments by showing that both tasks share common core computations supported by a left-lateralized brain network, but hand-tool compatibility task engages regions outside of this brain network and is explained by visual imagery while tool-tool task is rather explained by motor imagery. Our results shed a new light on action tool knowledge tasks.

Indexed as

BrainCognitionPsychomotor PerformanceAdultBrain MappingFemaleHandHumansMagnetic Resonance ImagingMaleMiddle AgedYoung Adult

Identifiers

PMID40181134
PMCPMC11968931

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.