ArticleLasers in medical science2025
Nanostructured lipid carriers containing pheophytins derived from Cnidoscolus quercifolius Pohl for photodynamic therapy against breast cancer: isolation, identification, characterization, in vitro activity, and in silico studies.
Brenda Maria Silva Bezerra, Mariana Rillo Sato, Igor José Dos Santos Nascimento, Ricardo Olímpio de Moura, Antonio Carlos Santos Rocha Junior, Harley da Silva Alves, João Augusto Oshiro-Junior
Abstract read
In one paragraphArticle in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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5 · Who and what moneyAuthors and funding
7 authors.
Brenda Maria Silva BezerraPharmaceutical Sciences Postgraduate Program, Center for Biological and Health Sciences, State University of Paraíba, Av. Juvêncio Arruda, S/N, Campina Grande, PB, 58429-500, Brazil.ORCID http://orcid.org/0000-0003-2610-3668 Mariana Rillo SatoPharmaceutical Sciences Postgraduate Program, Center for Biological and Health Sciences, State University of Paraíba, Av. Juvêncio Arruda, S/N, Campina Grande, PB, 58429-500, Brazil.ORCID http://orcid.org/0000-0002-6527-3937 Igor José Dos Santos NascimentoPharmaceutical Sciences Postgraduate Program, Center for Biological and Health Sciences, State University of Paraíba, Av. Juvêncio Arruda, S/N, Campina Grande, PB, 58429-500, Brazil.ORCID http://orcid.org/0000-0002-2664-4336 Ricardo Olímpio de MouraPharmaceutical Sciences Postgraduate Program, Center for Biological and Health Sciences, State University of Paraíba, Av. Juvêncio Arruda, S/N, Campina Grande, PB, 58429-500, Brazil.ORCID http://orcid.org/0000-0002-1590-3750 Antonio Carlos Santos Rocha JuniorPharmaceutical Sciences Postgraduate Program, Center for Biological and Health Sciences, State University of Paraíba, Av. Juvêncio Arruda, S/N, Campina Grande, PB, 58429-500, Brazil.
Harley da Silva AlvesPharmaceutical Sciences Postgraduate Program, Center for Biological and Health Sciences, State University of Paraíba, Av. Juvêncio Arruda, S/N, Campina Grande, PB, 58429-500, Brazil.ORCID http://orcid.org/0000-0002-7734-6857 João Augusto Oshiro-JuniorPharmaceutical Sciences Postgraduate Program, Center for Biological and Health Sciences, State University of Paraíba, Av. Juvêncio Arruda, S/N, Campina Grande, PB, 58429-500, Brazil. joaooshiro@yahoo.com.br.ORCID http://orcid.org/0000-0001-7247-1598 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
This study aimed to isolate and identify compounds with photodynamic activity from the ethanolic extract of Cnidoscolus quercifolius leaves, incorporate them into nanostructured lipid carriers (NLCs), evaluate singlet oxygen (
Indexed as
Breast NeoplasmsNanostructuresPheophytinsPhotochemotherapyPhotosensitizing AgentsCell SurvivalComputer SimulationDrug CarriersFemaleHumansLipidsMCF-7 CellsPlant ExtractsPlant LeavesSinglet OxygenDrug CarriersLipidsPheophytinsPhotosensitizing AgentsPlant ExtractsSinglet OxygenCancer treatmentChlorophyll derivatesLipid nanoparticlesMolecular DockingPhotodynamic therapy
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