ArticleBMJ open2025
Association of depressive symptoms with non-fatal cardiovascular disease in middle-aged and elderly patients with hypertension: a cohort study from China.
Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- The impact of hospital competition on healthcare quality: evidence from China's healthcare reform.Frontiers in public health · 2025Article
- Article
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7 authors.
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Abstract
objectiveOur study explored the association between depressive symptoms and non-fatal cardiovascular disease, as well as other significant risk factors for non-fatal cardiovascular disease, in middle-aged and elderly patients with hypertension in China.
designProspective cohort study.
settingData were sourced from the China Health and Retirement Longitudinal Study (CHARLS) database over a 9-year period (2011-2020).
participantsMiddle-aged and elderly patients with hypertension aged 45 and above in China. OUTCOME MEASURES: Non-fatal cardiovascular disease was ascertained based on self-reported, physician-diagnosed heart disease. Depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale-10.
resultsA total of 1755 participants were enrolled in the prospective cohort study. The incidence of non-fatal cardiovascular diseases among patients with hypertension was 5 per 1000 person-months. There was a positive linear correlation between depressive symptoms and the risk of non-fatal cardiovascular diseases (p
conclusionsThis study demonstrates graded associations between depression severity and incident non-fatal cardiovascular disease in middle-aged and elderly patients with hypertension in China. The multivariable analysis identified five modifiable risk determinants: inadequate health education, advanced age, female gender, diabetes comorbidity and hypertension exposure duration of 7-21 years. These findings necessitate precision prevention strategies combining psychocardiological interventions with risk factor modification in high-risk subgroups.
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