ArticleApplied clinical informatics2025
The Burden of a Highly Targeted Alert.
Article in Applied clinical informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Effectiveness of the Prospective Prescription Review System in Reducing Irrational Prescriptions at a Tertiary Specialty Hospital: Retrospective Cohort Study.JMIR formative research · 2026Article
- Integrating clinical decision support systems, nursing vigilance, and physician prescribing patterns to reduce preventable adverse drug events: a structured evidence-based narrative review on human-AI interface in medication safety.Frontiers in digital health · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interruptive alerts in clinical decision support (CDS) systems are intended to guide clinicians in making informed decisions and adhering to best practices. However, these alerts can often become a source of frustration, contributing to alert fatigue and clinician burnout. Traditionally, an alert's burden is often assessed by evaluating the total number of times it is seen by end-users, which can overlook the true impact of highly interruptive workflows. This study demonstrates how an alert burden metric was employed to pinpoint an ineffective and burdensome alert, ultimately leading to its deactivation.This study aimed to evaluate the effectiveness of a burden metric in identifying high-impact, low-value alerts and prioritizing improvement efforts for a CDS governance team.A clinical informatics team employed Phrase Health's "Phrase Burden Index" (PBI) to assess alert burden and identify areas requiring intervention within the alert library.The team used the PBI to identify a breast cancer survivorship alert that fired 3,550 times in 2023, with the desired alert action chosen in only 0.00056% of alert firings. An investigation identified that this alert targeted a single clinician over the span of several years, and the CDS governance team promptly decommissioned the alert.This case highlights the value of continuous CDS monitoring, effective governance, and advanced analytics to identify and mitigate alert fatigue. Insights from this failure provide guidance for enhancing future CDS design, evaluation, and clinician engagement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.