ReviewGynecologic oncology2025
Understanding frailty and the role of patient-centered care for older adults with gynecologic cancer.
Review in Gynecologic oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Age- and Treatment-Related Patterns in Fatigue, Coping/Resilience, and Skeletal Muscle Bioenergetics (Biomedicines · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The number of older adults with cancer will significantly grow in the coming decades. 45 % of older adults with gynecologic cancer are estimated to be affected by frailty. Frailty is a state of reduced physiologic reserve and decreased resiliency resulting in increased vulnerability to stressors. Importantly, frailty can exist in conjunction, but is not synonymous, with chronological age and older adults can be a heterogenous population. Routine assessment of frailty can help providers prevent both over- and under-treatment. The purpose of this review to describe the current state of literature on frailty as it relates to gynecologic cancer and draw from other literature including geriatrics, medical oncology, and surgery to suggest approaches to care. Frail patients have increased rates of surgical morbidity and mortality, higher toxicity to systemic therapy, and lower overall survival. Principles of the 5Ms (mobility, multi-complexity, mind, medications, and matters most) can be used in the clinic to guide care for older vulnerable (at risk) or frail adults. Surgical and medical oncology literature consistently indicates improved outcomes when multi-disciplinary approaches are used with routine frailty assessment. Future work is urgently needed to add validated geriatric measurements and outcomes into therapeutic trials and evaluate the impact of treatment choices on outcomes important to older adults such as functional recovery.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.