Evidence map›Paper›PMID 40179463›Full record

ReviewCurrent opinion in neurobiology2025

Body fluid regulation.

Yameng Zhang, Yuki Oka

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yameng ZhangDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Yuki OkaDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. Electronic address: yoka@caltech.edu.

Funding

Dissecting sodium appetite circuits in the mammalian brainR01NS123918 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI OKA, YUKI · 2021 to 2025
$2.0M
NINDS NIH HHS R01 NS123918
6 · The paper itself

Abstract

Maintaining the fluid balance requires complex crosstalk within the neural circuits and endocrine systems through the brain-body axis. Previous research focused on the thirst-driving pathways in the brain. Recent studies have shed more light on the role of postingestive feed-forward modulation mediated by peripheral signals. Advances in technology have unveiled the genetic profiles of the underlying circuits, enabling more precise interventions in future translational research. Despite the prevalence of fluid balance dysregulation in modern life, its health relevance remains underappreciated. In this review, we summarize the recent major findings in the field and describe common fluid-related disorders.

Indexed as

Body FluidsBrainWater-Electrolyte BalanceAnimalsHumans

Identifiers

PMID40179463
PMCPMC12162210

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.