Evidence map›Paper›PMID 40179240›Full record

ArticleAesthetic surgery journal2025

High-Intensity Focused Electrical Stimulation and Sync Radiofrequency+ Technology for Submental Volume Reduction: An MRI Study.

Barry DiBernardo, Carolyn Jacob, Lesley Clark-Loeser

Abstract read
In one paragraph

Article in Aesthetic surgery journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Barry DiBernardo
Carolyn Jacob
Lesley Clark-Loeser

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExcessive weight gain, aging-related skin laxity, and weakened digastric muscle contribute to the formation of submental fullness.

objectivesThe aim of this study was to investigate the efficacy and safety of combined high-intensity focused electrical stimulation (HIFES) and novel Synchronized Radiofrequency+ (Sync RF+) energies for submental volume reduction, and in addition to examine the effect of HIFES and Sync RF treatment on fat volume in the cheek area.

methodsThirty-three subjects (n = 33) received 4 treatments once weekly, on the submental and cheek area. Two- and three-dimensional photographs were taken at baseline, after the fourth treatment, and at both follow-ups at 1 and 3 months posttreatment. MRI scanning was performed at baseline, and at both follow-ups.

resultsThe overall submental volume decreased by 25.12% at 1 month and by 36.20% at 3 months. The submental fat decreased by 20.54% at 1 month and by 30.37% at 3 months. The mean [standard deviation] volume reduction evaluated from 3D photography was 3.48 [3.60] mL immediately after the fourth treatment, 5.39 [5.93] mL at 1 month, and 10.25 [5.40] mL at 3 months. The mean Clinician-Reported Submental Fat Rating Scale grade improved by 0.56 [0.42] points after the fourth treatment, by 0.85 [0.53] points at 1 month, and by 1.03 [0.50] points at 3 months. Overall, 84.8% of subjects found the treatment comfortable and 93.9% were satisfied with the treatment results.

conclusionsThe study findings suggest that this novel approach offers a notable option for submental volume reduction, indicating that HIFES and Sync RF+ technology is capable of aesthetic enhancement as well as skin and muscle improvement. LEVEL OF EVIDENCE: 4 (THERAPEUTIC):

Indexed as

Cosmetic TechniquesElectric Stimulation TherapyLipectomySubcutaneous FatAdultAgedCheekFemaleFollow-Up StudiesHumansImaging, Three-DimensionalMagnetic Resonance ImagingMaleMiddle AgedPatient SatisfactionPhotography

Identifiers

PMID40179240
PMCPMC12168439

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