Evidence map›Paper›PMID 40179206›Full record

Trial reportJournal of acquired immune deficiency syndromes (1999)2025

Cost-Effectiveness of a Tailored Pain Self-Management Intervention Compared With Enhanced Usual Care Among People With HIV and Chronic Pain: An Economic Evaluation.

Karlyn A Edwards, Kenneth J Smith, Katie Fitzgerald Jones, Matthew J Bair, Jane M Liebschutz, Lakeya S McGill, Deana Agil, Mallory O Johnson, Tammi Thomas, Olivio J Clay and 10 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of acquired immune deficiency syndromes (1999), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03692611 (Evaluation of the Efficacy and Mechanisms of a Novel Intervention for Chronic Pain Tailored to People Living With HIV), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03692611 nacompletednot on this map

Evaluation of the Efficacy and Mechanisms of a Novel Intervention for Chronic Pain Tailored to People Living With HIV

TypeinterventionalSponsorUniversity of PittsburghRan2019 to 2025Enrolled278ConditionsChronic PainArmsSkills TO Manage Pain (STOMP), Comparison group
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Karlyn A EdwardsDivision of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA.ORCID 0000-0002-5821-3733
Kenneth J SmithDivision of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA.
Katie Fitzgerald JonesNew England Geriatric Research Education and Clinical Center, Section of Palliative Care, VA Boston Healthcare System, Boston, MA.
Matthew J BairVA HSR Center for Health Information and Communication, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN.
Jane M LiebschutzDivision of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA.
Lakeya S McGillDivision of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA.
Deana AgilDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Mallory O JohnsonDivision of Prevention Science, Department of Medicine, University of California, San Francisco, San Francisco, CA.
Tammi ThomasDivision of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL.
Olivio J ClayDepartment of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL.
Claire E FarelDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Sonia NapravnikDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Dustin LongDepartment of Biostatistics, Wake Forest University, Winston-Salem, NC; and.
Greer BurkholderDivision of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL.
Lindsay BrowneDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Amy L DurrDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Bernadette JohnsonDivision of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL.
William DemonteVirginia Mason Franciscan Health, Bonney Lake, WA.
Sarah Margaret OrrisDivision of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA.
Jessica S MerlinDivision of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA.

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
University of Michigan (UM) HEAL Initiative National K12 Clinical Pain Career Development Program (UM-HCPDP)K12NS130673 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Daniel J Clauw, Steven Edward Harte · 2022 to 2026
$12.5M
University of Pittsburgh Collaboration in Addiction Training Scholars (PittCATS) ProgramK12DA050607 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jane M. Liebschutz, Erin L Winstanley · 2020 to 2026
$3.2M
Evaluation of the efficacy and mechanisms of a novel intervention for chronic pain tailored to people living with HIVR01MH115754 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MERLIN, JESSICA S · 2018 to 2022
$3.1M
Mentoring the next generation of researchers at the intersection of opioid use disorder and chronic painK24DA056837 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Megan Hamm, Jessica S Merlin · 2023 to 2026
$771k
National Institute of Health P30AI050410NHLBI NIH HHS L60 HL170453NIAID NIH HHS P30 AI050410NIDA NIH HHS K12050607NIDA NIH HHS K12 DA050607NIDA NIH HHS K24 DA056837NIDA NIH HHS K24DA056837NIMH NIH HHS 1R01MH115754-01A1NIMH NIH HHS R01 MH115754NINDS NIH HHS 1L60HL170453-01NINDS NIH HHS K12 NS130673NINDS NIH HHS K12NS130673
6 · The paper itself

Abstract

backgroundPain self-management (PSM) interventions are low risk, effective interventions for chronic pain that have high potential for scalability. Economic evaluations are a key component to assessing scalability. We evaluated the cost-effectiveness of a tailored PSM called Skills to Manage Pain (STOMP) as compared with enhanced usual care (EUC) among people with HIV and chronic pain. SETTING AND

methodsData are from a randomized controlled trial of STOMP (N = 278). From a health care perspective, a Markov decision analysis model for a 12-month time horizon was used. Participants were recruited from 2 academic medical centers within the Center for AIDS Research Network of Integrated Clinical Systems (CNICS) cohort. STOMP involves 6 individual sessions and 6 peer-led group sessions. The EUC control group received the STOMP treatment manual. The primary outcome was the incremental cost-effectiveness ratio, defined as US dollars per quality-adjusted life-year (QALY) gained derived from trial-based Medical Outcomes Study Short-Form 12 (SF-12) data. Sensitivity analyses examined the effects of parameters varied individually and collectively on model results.

resultsParticipants were middle-aged (M = 53.5, SD = 10), male (53%), and Black/African American (81%). Model calculation of effectiveness for the 12-month time horizon resulted in 0.570 QALYs for EUC and 0.603 QALYs for the STOMP intervention, or 0.033 QALYs gained by STOMP compared with EUC. In probabilistic sensitivity analyses that varied all parameters simultaneously, the STOMP intervention was favored in 98.0% of 10,000 model iterations at a $100,000/QALY threshold.

conclusionsSTOMP is a cost-effective and scalable PSM intervention for people with HIV and chronic pain.

trial registrationClinical Trials Registration #NCT03692611.

Indexed as

Chronic PainCost-Benefit AnalysisHIV InfectionsPain ManagementSelf-ManagementAdultFemaleHumansMaleMiddle AgedQuality-Adjusted Life Yearschronic paincost-effectivenesseconomic evaluationHIVpain self-management

Identifiers

PMID40179206
PMCPMC12885238

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.