Evidence map›Paper›PMID 40179166›Full record

ArticleScience (New York, N.Y.)2025

Beyond wear and tear at the joint.

Chuan-Ju Liu

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Ion channels as therapeutic targets in osteoarthritis.Trends in pharmacological sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Chuan-Ju LiuDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.

Funding

The immunological mechanism of PGRNs anti-inflammatory effect - Renewal - 1R01AR062207 · NIAMS · YALE UNIVERSITY · PI Chuanju Liu · 2012 to 2026
$5.6M
The Role of PGRN Growth Factor in Osteoarthritis. - Renewal - 1 - Revision - 2R01AR061484 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LIU, CHUANJU · 2011 to 2020
$4.8M
Progranulin: A Novel Gene in Gaucher DiseasesR01NS103931 · NINDS · YALE UNIVERSITY · PI Chuanju Liu, Ying Sun · 2017 to 2026
$4.3M
The Role of Sodium Channel Nav1.7 in Osteoarthritis - Resubmission - 1R01AR078035 · NIAMS · YALE UNIVERSITY · PI Chuanju Liu, Stephen Waxman · 2022 to 2026
$2.8M
Targeting TNF Receptors to Inhibit Inflammation and to Prompt Bone Regeneration in Type 1 Diabetes - Resubmission - 1R01AR076900 · NIAMS · YALE UNIVERSITY · PI LIU, CHUANJU · 2020 to 2024
$2.0M
NIAMS NIH HHS R01 AR061484NIAMS NIH HHS R01 AR062207NIAMS NIH HHS R01 AR076900NIAMS NIH HHS R01 AR078035NINDS NIH HHS R01 NS070328NINDS NIH HHS R01 NS103931
6 · The paper itself

Abstract

Bile acid metabolism meets glucagon-like peptide 1 signaling in osteoarthritis.

Indexed as

Bile Acids and SaltsCartilage, ArticularGlucagon-Like Peptide 1OsteoarthritisAnimalsHumansSignal TransductionBile Acids and SaltsGlucagon-Like Peptide 1

Identifiers

PMID40179166
PMCPMC12382341

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.