Evidence map›Paper›PMID 40179061›Full record

ArticlePloS one2025

Study protocol: LIAM Mc trial (Linking In with Advice and supports for Men impacted by Metastatic cancer).

Brendan Noonan, Philip Bredin, Anita M Cahill, Stephanie Corkery, Katie E Johnston, Katarina Medved, Anne Marie Cusack, Josephine Hegarty, Mohamad M Saab, Samantha J Cushen and 6 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05946993 (Linking In With Advice and Supports for Men Impacted by Metastatic Cancer), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05946993 naactive not recruitingnot on this map

Linking In With Advice and Supports for Men Impacted by Metastatic Cancer

TypeinterventionalSponsorUniversity College CorkRan2023 to 2026Enrolled72ConditionsSurvivorship, Prostate Cancer, Kidney Cancer, Urothelial Tract/Bladder Cancer, NosArmsPhysiotherapy, Dietitian Support, Nursing and Psychosocial
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Brendan NoonanCatherine McAuley School of Nursing and Midwifery University College Cork, Ireland.ORCID 0000-0002-1227-7045
Philip BredinMedical Oncology, Cork University Hospital, Ireland.ORCID 0000-0003-2560-8699
Anita M CahillUrology, Cork University Hospital, Ireland.
Stephanie CorkeryPhysiotherapy Department, Cork University Hospital, Ireland.
Katie E JohnstonSchool of Food and Nutritional Sciences, University College Cork, Ireland.
Katarina MedvedSchool of Public Health, University College Cork, Ireland.
Anne Marie CusackSchool of Public Health, University College Cork, Ireland.
Josephine HegartyCatherine McAuley School of Nursing and Midwifery University College Cork, Ireland.
Mohamad M SaabCatherine McAuley School of Nursing and Midwifery University College Cork, Ireland.
Samantha J CushenSchool of Food and Nutritional Sciences, University College Cork, Ireland.
Roisin ConnollyCancer Research @UCC, College of Medicine and Health, University College Cork, Ireland.
Brendan PalmerSchool of Public Health, University College Cork, Ireland.
Darren DahlyHealth Research Board Clinical Research Facility, University College Cork, Ireland.
Mike MurphySchool of Applied Psychology, University College Cork, Ireland.ORCID 0000-0002-8379-3813
Richard M BamburyMedical Oncology, Cork University Hospital, Ireland.
Jack P GleesonMedical Oncology, Cork University Hospital, Ireland.ORCID 0000-0001-6908-495X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe significant increase in cancer survivorship rates necessitates a comprehensive, multidisciplinary approach to supportive care services. This study seeks to assess the feasibility of introducing a Men's Health Initiative supportive care intervention program in Ireland.

methodsThis is a single-arm feasibility study involving a 12-week men's cancer survivorship programme alongside routine follow-up care in patients with advanced genitourinary malignancies. Men with advanced/metastatic genitourinary cancer (including prostate, kidney, urothelial tract, testicular or penile cancer), are eligible to enrol, with a target of 72 participants over a 2-year period. The intervention programme entails a twice-weekly physiotherapy-led exercise programme, along with dietetics, nursing, and psychosocial components, and regular signposting to additional available services. A Pilot Phase involving analysis of data from the first group of 6 participants to complete the programme is planned, before an Expansion Phase. Assessments will occur at baseline, on completion of the 12-week intervention, and 3 months post-intervention, and will include analyses of exercise/activity levels, body composition, muscle strength, psychological wellbeing, quality of life and resources utilised. The primary endpoints are to determine the feasibility and acceptability of introducing a men's cancer survivorship intervention programme into routine follow-up care in patients with advanced genitourinary malignancies. Secondary endpoints include impact of the intervention programme on quality of life, cancer-related fatigue, maintenance of weight, changes in body composition and changes in dietary intake and diet quality over the study period, as well as self-care agency and its relationship to quality of life and symptoms experienced. A qualitative process evaluation will be undertaken to explore participants' experiences, while an economic analysis will examine the healthcare resource utilization and costs associated with the intervention. The trial was peer-reviewed by the Irish Cancer Society. DISCUSSION: The programme described in this protocol provides a supportive and safe environment for the introduction of self-care interventions using a small group-based format supported by individualised counselling according to the participant's identified needs. The development and implementation of future supportive care programmes for men's cancer survivorship will be guided by the findings of this study. TRIAL REGISTRARTION: ClinicalTrials.gov NCT05946993.

Indexed as

Urogenital NeoplasmsCancer SurvivorsClinical Trials as TopicExerciseExercise TherapyFeasibility StudiesHumansIrelandMaleMiddle AgedNeoplasm MetastasisPilot ProjectsQuality of Life

Identifiers

PMID40179061
PMCPMC11967965

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.