Evidence map›Paper›PMID 40178703›Full record

ReviewCurrent cardiology reports2025

Updates in Diagnosis and Treatment of Immune Checkpoint Inhibitor Myocarditis.

Anthony M Hachem, Aditya Desai, Noah Beinart, Keila C Ostos-Mendoza, Ana Sofia Lopez Rodriguez, Regina Diaz de Leon Derby, Sara Ebrahimi, Nicolas L Palaskas

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anthony M HachemUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.
Aditya DesaiUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.
Noah BeinartUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.
Keila C Ostos-MendozaUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ana Sofia Lopez RodriguezUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.
Regina Diaz de Leon DerbyUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.
Sara EbrahimiUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.
Nicolas L PalaskasUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA. NLPalaskas@mdanderson.org.

Funding

Cancer Prevention and Research Institute of Texas RP200670
6 · The paper itself

Abstract

purpose of reviewTo provide an update on the literature regarding diagnosis and management of immune checkpoint inhibitor myocarditis. RECENT

findingsThe diagnosis of immune checkpoint inhibitor myocarditis has evolved to include more reliance on performing endomyocardial biopsy to clarify the diagnosis in selected cases. Additionally, there is recognition of a spectrum of disease both clinically and on endomyocardial biopsy suggesting that there is a range of severity from mild to fulminant. The treatment of immune checkpoint inhibitor myocarditis is shifting towards increased use of additional immunosuppressive medications as steroid sparing agents. There are increased studies including two randomized controlled trials evaluating abatacept in the treatment of immune checkpoint inhibitor myocarditis. This review summarizes the latest literature regarding diagnosis and management of immune checkpoint inhibitor myocarditis and provides our experience and approach to this rare but potentially fatal condition.

Indexed as

Immune Checkpoint InhibitorsImmunosuppressive AgentsMyocarditisAbataceptBiopsyHumansMyocardiumAbataceptImmune Checkpoint InhibitorsImmunosuppressive AgentsDiagnosisImmune checkpoint inhibitorsImmunotherapyMyocarditisTreatment

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.