Evidence map›Paper›PMID 40178618›Full record

ArticleSurgical and radiologic anatomy : SRA2025

Influence of variations of craniovertebral junction anatomy on safe C1 lateral mass and C2 pedicle screw insertion: a cadaveric and radiologic study.

Derya Karatas, Ahmet Dagtekin, Saygi Uygur, Irmak Tekeli Barut, Engin Kara, Kaan Esen, Emel Avci, Mustafa Kemal Baskaya

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Article in Surgical and radiologic anatomy : SRA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Derya KaratasDepartment of Neurosurgery, Mersin University Faculty of Medicine, Mersin, Türkiye. k_derya@yahoo.com.
Ahmet DagtekinDepartment of Neurosurgery, Mersin University Faculty of Medicine, Mersin, Türkiye.
Saygi UygurDepartment of Neurosurgery, Kadirli State Hospital, Osmaniye, Türkiye.
Irmak Tekeli BarutDepartment of Neurosurgery, Mersin University Faculty of Medicine, Mersin, Türkiye.
Engin KaraDepartment of Radiology, Mersin University Faculty of Medicine, Mersin, Türkiye.
Kaan EsenDepartment of Radiology, Mersin University Faculty of Medicine, Mersin, Türkiye.
Emel AvciDepartment of Neurosurgery, Mersin University Faculty of Medicine, Mersin, Türkiye.
Mustafa Kemal BaskayaDepartment of Neurosurgery, University of Wisconsin-Madison School of Medicine and Public Health, Madison, USA.

Funding

Mersin University scientific research projects coordination unit BAP 2018-2-TP3-2997
6 · The paper itself

Abstract

purposeThe aim of the present study is to analyze the feasibility of a new optimized C1 lateral mass and C2 pedicle screw method that has a suitable trajectory for a range of anatomical variations to decrease the risk of vertebral artery injury.

methodsThe craniovertebral junction of 17 cadavers (34 sides) were dissected after performing thin-cut computed tomography. The screw entry points, targets, angles, and lengths of the trajectories were performed for C1 lateral mass and C2 pedicle. We particularly focused on the morphometric features and the safety of trajectories in cadavers with vascular and bony variations.

resultsFor the C1 lateral mass, the ideal medial and cranial angles were 13.4° ± 1.0° and 14.7° ± 1.1°, respectively. For the C2 pedicle screw, the cranial and medial angles were 27.7° ± 1.4° and 20.4° ± 1.5°, respectively. High-riding vertebral arteries (HRVA) were observed in 35.3% of all cadavers. The incidence of an arcuate foramen was 47% among all sides and its coexistence with an HRVA among all cadavers was 23.5%.

conclusionPreoperative pedicle-oriented radiological evaluation is crucial before C1 lateral mass and C2 pedicle screw placement because of the high incidence of bony and vascular variations. Using our safe C2 pedicle trajectory, a longer and safer screw course that preserves the vertebral artery can be achieved with a more feasible cranial angle, even with HRVAs, with the exception of narrow pedicle anatomy.

Indexed as

Anatomic VariationCervical VertebraePedicle ScrewsSpinal FusionVertebral ArteryAgedAged, 80 and overCadaverCervical AtlasFeasibility StudiesFemaleHumansMaleMiddle AgedTomography, X-Ray ComputedVascular System InjuriesArcuate foramenC1 lateral massC2 pedicleComputed tomographyHigh riding vertebral artery

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.