Evidence map›Paper›PMID 40178058›Full record

ArticleEmergency medicine Australasia : EMA2025

Opioid overdoses following use of cocaine and methamphetamine in New South Wales, and the public health responses.

Peter Chisholm, Jared Brown, Thanjira Jiranantakan, Mary Ellen Harrod, Catherine McDonald, Una Cullinan, Darren M Roberts

Abstract read
In one paragraph

Article in Emergency medicine Australasia : EMA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peter ChisholmCentre for Alcohol and Other Drugs, New South Wales Ministry of Health, Sydney, New South Wales, Australia.ORCID 0000-0002-5270-2798
Jared BrownCentre for Alcohol and Other Drugs, New South Wales Ministry of Health, Sydney, New South Wales, Australia.ORCID 0000-0001-6855-3865
Thanjira JiranantakanCentre for Alcohol and Other Drugs, New South Wales Ministry of Health, Sydney, New South Wales, Australia.ORCID 0000-0002-9546-1939
Mary Ellen HarrodNSW Users and AIDS Association, Sydney, New South Wales, Australia.ORCID 0000-0001-8763-3115
Catherine McDonaldNSW Health Pathology, Forensic & Analytical Science Service, Forensic Toxicology Laboratory, Lidcombe, New South Wales, Australia.ORCID 0000-0003-3745-6653
Una CullinanNSW Health Pathology, Forensic & Analytical Science Service, Illicit Drug Analysis Unit, Lidcombe, New South Wales, Australia.
Darren M RobertsNew South Wales Poisons Information Centre, Sydney Children's Hospitals Network, Sydney, New South Wales, Australia.ORCID 0000-0001-9101-7577

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRecent years have seen sporadic reports in Australia of stimulants being contaminated with opioids. Since late 2023, there has been an increase in opioid overdoses among individuals in New South Wales (NSW) using substances believed to be cocaine or methamphetamine. We analysed the frequency and characteristics of these cases and describe our public health responses.

methodsThe Prescription, Recreational & Illicit Substance Evaluation (PRISE), operated by NSW health since July 2018, is a statewide surveillance, epidemiology, and toxicity response programme. We did a retrospective analysis of each case of opioid toxicity following use of cocaine or methamphetamine submitted to the PRISE programme from January 2022 to June 2024, categorising cases into confirmed, probable, and suspected.

resultsThirty-four cases were found, 19 involving cocaine and 15 involving methamphetamine. Twenty-two (65%) were classified as confirmed, and 12 (35%) as probable. There were two deaths (6%). Twenty-three cases (68%) were in Sydney. Multiple stakeholders reviewed trends and formulated public health responses, leading to the distribution of public drug warnings and media releases in November 2023 and February 2024 because of ongoing case detections.

conclusionsThe increase in detections, which continued in the months following the public health responses, underscores the need for comprehensive surveillance, response, monitoring, and reporting of this phenomenon in NSW. Engagement with clinicians and the community is essential for the success of this programme.

Indexed as

CocaineMethamphetamineOpiate OverdosePublic HealthAdolescentAdultAgedFemaleHumansMaleMiddle AgedNew South WalesRetrospective StudiesCocaineMethamphetaminedrug contaminationdrug epidemiologydrug substitutiondrug surveillanceopioid overdose

Identifiers

PMID40178058
PMCPMC11967155

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.