Evidence map›Paper›PMID 40178030›Full record

ArticleJournal of biophotonics2025

Evaluating the Intensity of Muscle Contraction by Near-Infrared Spectroscopy, a Potential Application for Scaling Muscle Spasm.

Mehdi Nourizadeh, Yekta Saremi, Amir Parham Pirhadi Rad, Sepideh Mortezanezhad, Iman Amani Tehrani, Jocelyn Bégin, Maria Juricic, Kishore Mulpuri, Babak Shadgan

Abstract read
In one paragraph

Article in Journal of biophotonics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mehdi NourizadehInternational Collaboration on Repair Discoveries, Vancouver, Canada.ORCID 0000-0002-2523-3199
Yekta SaremiInternational Collaboration on Repair Discoveries, Vancouver, Canada.
Amir Parham Pirhadi RadInternational Collaboration on Repair Discoveries, Vancouver, Canada.
Sepideh MortezanezhadInternational Collaboration on Repair Discoveries, Vancouver, Canada.
Iman Amani TehraniInternational Collaboration on Repair Discoveries, Vancouver, Canada.
Jocelyn BéginInternational Collaboration on Repair Discoveries, Vancouver, Canada.
Maria JuricicDepartment of Physical Therapy, University of British Columbia, Vancouver, Canada.
Kishore MulpuriDepartment of Orthopaedics, University of British Columbia, Vancouver, Canada.
Babak ShadganInternational Collaboration on Repair Discoveries, Vancouver, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Muscle spasticity, common in conditions such as cerebral palsy, spinal cord injury, and multiple sclerosis, is traditionally assessed using the Modified Ashworth Scale, which lacks consistency. This study evaluates near-infrared spectroscopy (NIRS) as a non-invasive tool for measuring muscle contraction intensity. Thirty-seven healthy adults performed isometric contractions at varying intensities (15%, 30%, 45%, and 60% of maximal voluntary contraction), with NIRS sensors monitoring changes in the Tissue Oxygenation Index (TOI) and electromyography (EMG) measuring muscle activity. Results demonstrated a significant negative correlation between contraction intensity and ΔTOI, indicating that higher contraction levels resulted in greater reductions in muscle oxygenation. Additionally, a multinomial logistic regression model confirmed that TOI could reliably predict contraction intensity (p < 0.001). This technique could provide real-time, objective data for spasticity assessment, potentially improving treatment plans.

Indexed as

Muscle ContractionMuscle SpasticityAdultElectromyographyFemaleHumansMaleOxygenSpectroscopy, Near-InfraredYoung AdultOxygenelectromyographymuscle contractionnear infrared spectroscopyspasticitytissue oxygenation

Identifiers

PMID40178030
PMCPMC12318644

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.