Evidence map›Paper›PMID 40177942›Full record

ArticleThe Gerontologist2025

Triadic Primary Care Encounters Managing Medications Among Individuals With Mild Cognitive Impairment and Dementia: Patient, Caregiver, and Clinician Perspectives.

Rachel O'Conor, Allison Pack, Andrea M Russell, Dianne Oladejo, Emily Rogalski, Darby Morhardt, Richard H Fortinsky, Lee A Lindquist, Stephen D Persell, Michael S Wolf

Abstract read
In one paragraph

Article in The Gerontologist, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rachel O'ConorDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0001-5104-9531
Allison PackDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Andrea M RussellDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0001-6869-9581
Dianne OladejoDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Emily RogalskiHealthy Aging & Alzheimer's Research Care (HAARC) Center, Department of Neurology, The University of Chicago, Chicago, Illinois, USA.
Darby MorhardtMesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University, Chicago, Illinois, USA.
Richard H FortinskyUConn Center on Aging, University of Connecticut School of Medicine, Farmington, Connecticut, USA.
Lee A LindquistDivision of Geriatrics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Stephen D PersellDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Michael S WolfDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Management of Complex Medication Regimens among Older Adults with Alzheimer's Disease and Related Dementias and their CaregiversK01AG070107 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI O'CONOR, RACHEL · 2021 to 2025
$685k
Alzheimer's Disease Core Center P30AG013854NCATS NIH HHS UL1TR001422NIA NIH HHS K01AG070107NIH HHS
6 · The paper itself

Abstract

BACKGROUND AND

objectivesIndividuals with mild cognitive impairment (MCI) or dementia work with family caregivers and clinicians to manage multidrug regimens; however, problems with medication management are common and contribute to avoidable hospitalizations among individuals with dementia. We sought to describe the initiation of these triadic clinical encounters and medication management to identify opportunities to enhance them. RESEARCH DESIGN AND

methodsWe conducted semi-structured qualitative interviews among individuals with MCI or dementia, their family caregivers, and primary care clinicians. Clinicians were not required to provide care for enrolled patients. Interview guides were informed by the Triadic Dementia Care Framework. Transcripts were analyzed following the Framework Method.

resultsWe enrolled 32 patients, 32 caregivers, and 25 clinicians. Patients, caregivers, and clinicians all prioritized patient-focused clinical encounters and noted transitions in medication management responsibilities typically occur after observing reduced patient capacity. During these transitions, clinicians noted they do not routinely provide an overview of their patients' medications to caregivers, yet caregivers expressed desire for this. Three cross-cutting themes also emerged: (a) balancing patient cognitive impairment limitations and retention of patient autonomy is important to all members of the triad; (b) historical relationship dynamics inform current clinical encounters and medication management; (c) additional time is needed to manage patients with multiple conditions and medications. DISCUSSION AND IMPLICATIONS: Opportunities exist to utilize a multidisciplinary care team to initiate thoughtful early planning for transitions in medication management responsibilities and provide supplemental counseling and materials that reiterate the value of triadic relationships, and detail patient-medication guidance.

Indexed as

CaregiversCognitive DysfunctionDementiaMedication Therapy ManagementPrimary Health CareAgedAged, 80 and overFemaleHumansInterviews as TopicMaleMiddle AgedQualitative ResearchMultiple chronic conditionsSelf-managementTransitions

Identifiers

PMID40177942
PMCPMC12314596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.