Evidence map›Paper›PMID 40177856›Full record

ArticleObesity (Silver Spring, Md.)2025

Clustering of intuitive eating and psychological health identifies subgroups associated with weight loss following semaglutide.

Antoine Avignon, Jean-Baptiste Bonnet, Jean Anitcheou, Sarah Tournayre, Vincent Attalin, Catherine Boegner, Abdulkader Jalek, Dominique Jullien, Camille Le Rouzic, Justine Myzia and 4 more

Abstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Antoine AvignonNutrition-Diabetes Department, University Hospital of Montpellier, Montpellier, France.
Jean-Baptiste BonnetNutrition-Diabetes Department, University Hospital of Montpellier, Montpellier, France.
Jean AnitcheouJoint Research Unit (UMR) 1302, Desbrest Institute of Epidemiology and Public Health, University of Montpellier, INSERM, Montpellier, France.
Sarah TournayreNutrition-Diabetes Department, University Hospital of Montpellier, Montpellier, France.
Vincent AttalinNutrition-Diabetes Department, University Hospital of Montpellier, Montpellier, France.
Catherine BoegnerNutrition-Diabetes Department, University Hospital of Montpellier, Montpellier, France.
Abdulkader JalekNutrition-Diabetes Department, University Hospital of Montpellier, Montpellier, France.
Dominique JullienNutrition-Diabetes Department, University Hospital of Montpellier, Montpellier, France.
Camille Le RouzicNutrition-Diabetes Department, University Hospital of Montpellier, Montpellier, France.
Justine MyziaNutrition-Diabetes Department, University Hospital of Montpellier, Montpellier, France.
Lucile MartyNutrition-Diabetes Department, University Hospital of Montpellier, Montpellier, France.
Youadigue KembaNutrition-Diabetes Department, University Hospital of Montpellier, Montpellier, France.
Ariane SultanNutrition-Diabetes Department, University Hospital of Montpellier, Montpellier, France.
Jean BousquetInstitute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveObesity management requires personalized approaches. Using data from the Aviitam platform in France, this study aimed to do the following: 1) explore psychological and behavioral patterns through clustering techniques; 2) validate the robustness of these clusters; and 3) assess their association with weight-loss outcomes in severe obesity under semaglutide treatment.

methodsPhase 1 included 989 adults with BMI ≥ 25 kg/m

resultsThe following two clusters were identified: the Intuitive Eaters Group (IEG, n = 482); and the Emotionally Driven Eaters Group (EDEG, n = 507). The IEG exhibited lower emotional distress and higher intuitive eating scores. HADS and IES-2 distinguished clusters effectively (area under the curve, 0.95). Robustness was confirmed in Phase 2. In Phase 3, the IEG demonstrated a significantly more favorable weight-loss trajectory compared to the EDEG (p = 0.03).

conclusionsPsychological and behavioral clusters identified through HADS and IES-2 are associated with weight loss under semaglutide treatment, suggesting the value of integrating psychological and behavioral profiling into obesity care.

Indexed as

Anti-Obesity AgentsFeeding BehaviorGlucagon-Like PeptidesMental HealthObesityObesity, MorbidWeight LossAdultBody Mass IndexCluster AnalysisFemaleFranceGlucagon-Like Peptide 1HumansMaleMiddle AgedAnti-Obesity AgentsGlucagon-Like Peptide 1Glucagon-Like PeptidesSemaglutide

Identifiers

PMID40177856
PMCPMC12015648

What OpenQuestion holds

Texttitle and abstract
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.