Evidence map›Paper›PMID 40177851›Full record

ArticlePsychophysiology2025

Anxiety Sensitivity and Intolerance of Uncertainty Uniquely Explain the Association of the Late Positive Potential With Generalized Anxiety Disorder Symptoms.

Matt R Judah, Hannah C Hamrick, Benjamin Swanson, Morgan S Middlebrooks, Grant S Shields

Abstract read
In one paragraph

Article in Psychophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Worry undermines savoring's ability to reduce negative picture processing.Cognitive, affective & behavioral neuroscience · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matt R JudahDepartment of Psychological Science, University of Arkansas, Fayetteville, Arkansas, USA.ORCID 0000-0003-3825-6821
Hannah C HamrickDepartment of Psychological Science, University of Arkansas, Fayetteville, Arkansas, USA.ORCID 0000-0002-8840-8734
Benjamin SwansonDepartment of Psychological Science, University of Arkansas, Fayetteville, Arkansas, USA.ORCID 0009-0007-3887-9128
Morgan S MiddlebrooksDepartment of Psychological Science, University of Arkansas, Fayetteville, Arkansas, USA.ORCID 0000-0002-4468-8199
Grant S ShieldsDepartment of Psychological Science, University of Arkansas, Fayetteville, Arkansas, USA.ORCID 0000-0002-0827-4669

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies suggest that generalized anxiety disorder (GAD) symptoms are related to late positive potential (LPP) responses to negative images, suggesting greater attention. Anxiety sensitivity (AS) and intolerance of uncertainty (IU) are cognitive factors in GAD vulnerability that may be activated by negative stimuli, thereby explaining why the LPP and GAD symptoms are related. We examined whether AS and IU explain the association of the LPP with GAD symptoms. Eighty-seven (77% women) young adults viewed 60 negative and 60 neutral images. The LPP was examined using both frequentist and Bayesian approaches. This revealed unique indirect effects of the LPP on GAD symptoms through AS and IU. Neither indirect effect was stronger, and the indirect effects were present regardless of using frequentist or Bayesian analyses or quantifying the LPP using residual-based scores or difference scores. The indirect effects predicted not only GAD symptoms but social anxiety and depression as well, consistent with the role of AS and IU in transdiagnostic vulnerability. The findings support AS and IU as links that explain how attention to negative stimuli is related not only to GAD symptoms but to other internalizing symptoms as well.

Indexed as

AnxietyAnxiety DisordersAttentionEvoked PotentialsAdolescentAdultElectroencephalographyFemaleGeneralized Anxiety DisorderHumansMaleUncertaintyYoung Adultanxiety sensitivitygeneralized anxiety disorderintolerance of uncertaintylate positive potential

Identifiers

PMID40177851
PMCPMC11966597

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.