Evidence map›Paper›PMID 40177747›Full record

ArticleCirculation. Cardiovascular imaging2025

Angiography-Derived Microcirculatory Resistance in Detecting Microvascular Obstruction and Predicting Heart Failure After STEMI.

Guanyu Lu, Lei Zhao, Keyao Hui, Zhihui Lu, Xiaoli Zhang, Hai Gao, Xiaohai Ma

Abstract read
In one paragraph

Article in Circulation. Cardiovascular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Reperfusion injury in STEMI: a double-edged sword.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guanyu Lu *Department of Interventional Diagnosis and Treatment (G.L., K.H., Z.L., X.M.), Beijing Anzhen Hospital, Capital Medical University, China.ORCID 0000-0002-2654-3500
Lei Zhao *Department of Radiology (L.Z.), Beijing Anzhen Hospital, Capital Medical University, China.ORCID 0000-0002-0619-6038
Keyao HuiDepartment of Interventional Diagnosis and Treatment (G.L., K.H., Z.L., X.M.), Beijing Anzhen Hospital, Capital Medical University, China.ORCID 0009-0002-9169-1937
Zhihui LuDepartment of Interventional Diagnosis and Treatment (G.L., K.H., Z.L., X.M.), Beijing Anzhen Hospital, Capital Medical University, China.ORCID 0009-0006-4568-5869
Xiaoli ZhangDepartment of Nuclear Medicine, Molecular Imaging Laboratory (X.Z.), Beijing Anzhen Hospital, Capital Medical University, China.
Hai GaoDepartment of Cardiology, Emergency Coronary Artery Unit (H.G.), Beijing Anzhen Hospital, Capital Medical University, China.
Xiaohai MaDepartment of Interventional Diagnosis and Treatment (G.L., K.H., Z.L., X.M.), Beijing Anzhen Hospital, Capital Medical University, China.ORCID 0000-0003-1259-0119

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicrovascular obstruction (MVO) is associated with heart failure (HF) following ST-segment-elevation myocardial infarction. Angiography-derived microcirculatory resistance (AMR), a wire- and adenosine-free measure, may facilitate early assessment of microvascular function post-primary percutaneous coronary intervention. This study aimed to evaluate the ability of AMR to detect MVO and its prognostic value for predicting HF in patients with ST-segment-elevation myocardial infarction post-primary percutaneous coronary intervention.

methodsPatients with consecutive ST-segment-elevation myocardial infarction undergoing primary percutaneous coronary intervention with a cardiac magnetic resonance examination 2 to 7 days post-procedure between April 2016 and February 2023 were retrospectively reviewed. AMR was computed from coronary angiography. MVO was identified and quantified via cardiac magnetic resonance. The end point was new-onset HF during follow-up.

resultsOverall, 475 patients (aged 56.8±11.7 years; 399 men) were included. The area under the curve for AMR to detect MVO was 0.821 (95% CI, 0.782-0.859), with an optimal cutoff value of 2.7 mm Hg*s/cm. During a median follow-up of 37.3 months, 121 (25.5%) patients developed HF. AMR, whether as a continuous (per 0.5-mm Hg*s/cm increase; hazard ratio, 1.29 [95% CI, 1.10-1.52];

conclusionsAMR showed good diagnostic performance in detecting MVO and was an independent and incremental predictor of HF in patients with ST-segment-elevation myocardial infarction post-primary percutaneous coronary intervention.

Indexed as

Coronary AngiographyCoronary CirculationHeart FailureMicrocirculationPercutaneous Coronary InterventionST Elevation Myocardial InfarctionVascular ResistanceAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective Studiesangiographyheart failuremagnetic resonance imagingmyocardial reperfusionprognosis

Identifiers

PMID40177747
PMCPMC12091217

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.