ArticleIBRO neuroscience reports2025
Height-dependent variation in corticospinal excitability modulation after active but not sham intermittent theta burst stimulation.
Article in IBRO neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Poor reproducibility and high inter-individual variability in responses to intermittent theta burst stimulation (iTBS) of the human motor cortex (M1) are matters of concern. Here we recruited 17 healthy young adults in a randomized, sham-controlled, crossover study. Transcranial magnetic stimulation (TMS)-elicited motor evoked potentials (MEPs) were measured pre-iTBS (T0) and post-iTBS at 4-7 (T1), 9-12 (T2), 17-20 (T3), and 27-30 minutes (T4) from the right first dorsal interosseous muscle. MEP grand average (MEPGA) was defined as the mean of the normalized-to-baseline MEPs at all timepoints post-iTBS. As secondary objectives, we measured blood pressure, heart rate, and capillary blood glucose pre-iTBS, and at 0 and 30 minutes post-iTBS. The TMSens_Q structured questionnaire was filled out at the end of each session. Two-way repeated ANOVA did not show a significant TIME×INTERVENTION interaction effect on MEP amplitude, MEP latency, blood pressure, heart rate, and blood glucose (p > 0.05). Sleepiness was the most reported TMSens_Q sensation (82.3 %) in both groups. Surprisingly, the subjects' height negatively correlated with the normalized MEP amplitudes at T3 (r = -0.65, p = 0.005), T4 (r = -0.66, p = 0.004), and MEPGA (r = -0.68, p = 0.003), with a trend correlation at T1 (r = -0.46, p = 0.062) and T2 (r = -0.46, p = 0.065) in the active but not sham group. In view of this, we urge future studies to delve deeper into the influence of height on neuroplasticity induction of the M1 representation of peripheral muscles. In the end, we highlight unique methodological considerations in our study protocol and future recommendations for M1-iTBS studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.